“Theranekron: A Novel Anti-inflammatory Candidate for Acetic Acid-Induced Colonic Inflammation in Rats”

Savran, Mehtap; Aşçı, Halil; Erzurumlu, Yalçın; Özmen, Özlem; İlhan, İlter; Sırın, M. Cem; KARAKUYU, Nasıf Fatih; Karaibrahimoğlu, Adnan

doi:10.1007/s11033-022-07722-5

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…Additionally, the chromogen diaminobenzidine was utilised. Negative controls were performed using an antigen dilution solution rather than a main antibody (Ağırca, 2020; Anter et al ., 2022; Savran et al ., 2022).…”

Section: Methodsmentioning

confidence: 99%

Prophylaxis effects of water kefir on post‐infectious irritable bowel syndrome in rat model

Gökırmaklı

Erol

Gün

et al. 2023

Int J of Food Sci Tech

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Water kefir (WK) is produced using WK grains containing beneficial bacteria and yeasts. It has antibacterial, anti-inflammatory, anti-diabetic, anti-hyperlipidaemic, anti-ulcerogenic, and antioxidant effects. The purpose of the research was to determine the effect of WK on irritable bowel syndrome (IBS). In this study, thirty-two female Wistar-Albino rats aged 3 months were randomly distributed to four groups: the control group (C), the WK group, the WK group with IBS (WK + IBS), and the IBS group. Results indicated that the IBS groups had higher white blood cell, lymphocyte, monocyte counts, and procalcitonin levels. The findings of WK + IBS group showed that WK improved against IBS. TNF-a, NF-kB expressions, and histopathological results significantly decreased after receiving WK treatment. In conclusion, ingestion of WK has prophylactic effects on IBS as exhibited through an in-vivo murine model. The findings suggested that IBS may be prevented and treated with WK.

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Section: Methodsmentioning

confidence: 99%