This Special Issue of Evolutionary Anthropology grew out of a symposium at the 2012 Society for American Archaeology (SAA) meeting in Memphis, Tennessee (April 18-22). The goal of the symposium was to explore what we will argue is one of the most important and promising opportunities in the global archeological enterprise. In late prehistoric North America, the initial rise of cultures of strikingly enhanced complexity and the local introduction of a novel weapon technology, the bow, apparently correlate intimately in a diverse set of independent cases across the continent, as originally pointed out by Blitz. If this empirical relationship ultimately proves robust, it gives us an unprecedented opportunity to evaluate hypotheses for the causal processes producing social complexity and, by extension, to assess the possibility of a universal theory of history. The rise of comparably complex cultures was much more recent in North America than it was elsewhere and the resulting fresher archeological record is relatively well explored. These and other features make prehistoric North America a unique empirical environment. Together, the symposium and this issue have brought together outstanding investigators with both empirical and theoretical expertise. The strong cross-feeding and extended interactions between these investigators have given us all the opportunity to advance the promising exploration of what we call the North American Neolithic transitions. Our goal in this paper is to contextualize this issue.