“…As a result of the interaction between K 2 [PtCl 4 ] and C≡NMe and the following addition of hydrazine, the first complex of a heteroatom-stabilized carbene was obtained [ 46 , 47 , 48 , 49 ]. Since that time, the metal-mediated addition of the monofunctional O- [ 50 , 51 , 52 , 53 , 54 ], N- [ 34 , 35 , 36 , 37 , 41 , 43 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 ], and other [ 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 ] nucleophiles as well as bifunctional nucleophiles [ 27 , 34 , 53 , 62 , 64 , 79 , 80 , 81 , 82 , …”