Abstract:Super-resolution microscopy and single molecule fluorescence spectroscopy require complementary and mutually exclusive experimental strategies that optimize either spatial or temporal resolution, making their combined implementation a challenge. With a GPU-driven, camera-based measurement strategy we demonstrate that it is possible to achieve this in 5 minutes (including measurement time) using the epidermal growth factor receptor (EGFR) as our model. EGFR, a transmembrane receptor tyrosine kinase, is a crucia… Show more
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