Theoretical calculations of dose distributions for beta‐ray eye applicators

Hokkanen, J.E.I.; Heikkonen, Jorma; Holmberg, P.

doi:10.1118/1.597927

Cited by 25 publications

(21 citation statements)

References 11 publications

(6 reference statements)

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“…Initially, some researchers measured the absorbed dose distribution using different methods such as ionization chambers, diamond detectors, or thermoluminescent dosimeters. Later, a point-kernel numerical method was used to calculate the dose distribution around a curved radiation source with the shape of a spherical shell [9] . Other researchers combined the point-kernel and the Monte Carlo method [10,11] .…”

Section: Introductionmentioning

confidence: 99%

Monte Carlo Estimation of Absorbed Dose Distributions Obtained from Heterogeneous 106Ru Eye Plaques

Zaragoza¹,

Eichmann²,

Flühs³

et al. 2017

Ocul Oncol Pathol

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Background: The distribution of the emitter substance in ¹⁰⁶Ru eye plaques is usually assumed to be homogeneous for treatment planning purposes. However, this distribution is never homogeneous, and it widely differs from plaque to plaque due to manufacturing factors. Methods: By Monte Carlo simulation of radiation transport, we study the absorbed dose distribution obtained from the specific CCA1364 and CCB1256 ¹⁰⁶Ru plaques, whose actual emitter distributions were measured. The idealized, homogeneous CCA and CCB plaques are also simulated. Results: The largest discrepancy in depth dose distribution observed between the heterogeneous and the homogeneous plaques was 7.9 and 23.7% for the CCA and CCB plaques, respectively. In terms of isodose lines, the line referring to 100% of the reference dose penetrates 0.2 and 1.8 mm deeper in the case of heterogeneous CCA and CCB plaques, respectively, with respect to the homogeneous counterpart. Conclusions: The observed differences in absorbed dose distributions obtained from heterogeneous and homogeneous plaques are clinically irrelevant if the plaques are used with a lateral safety margin of at least 2 mm. However, these differences may be relevant if the plaques are used in eccentric positioning.

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Section: Introductionmentioning

confidence: 99%

Monte Carlo Estimation of Absorbed Dose Distributions Obtained from Heterogeneous 106Ru Eye Plaques

Zaragoza¹,

Eichmann²,

Flühs³

et al. 2017

Ocul Oncol Pathol

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“…[14]. Epibulbäre Strontium-Applikatoren werden schon lange für die Behandlung von Tumoren und Pterygien der Bindehaut benutzt (Übersicht [23]).…”

Section: Episklerale Brachytherapieunclassified

Stellungnahme der Retinologischen Gesellschaft, der Deutschen Ophthalmologischen Gesellschaft und des Berufsverbands der Augenärzte Deutschlands zur Strahlentherapie bei neovaskulärer altersabhängiger Makuladegeneration

Gesellschaft

Gesellschaft²,

Deutschlands

2015

Ophthalmologe

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“…(Maigne, 2005 ;Maigne et al, 2004 ;Masurier, 1999 ;Mobit et Badragan, 2004 ;Nath et al, 1995 ;Soares et al, 2001 ;Tjho-Heslinga et al, 1999). Les résultats obtenus avec la version 1.2.0 de GATE (adaptée à geant4.6.2.p02) ont été comparés aux calculs théoriques de la méthode de Hokkanen (Hokkanen et al, 1997) Les incertitudes assignées à ces mesures sont évaluées à ±20 %. La figure 3 représente les comparaisons de doses pour les applicateurs CCA, CCB.…”

Section: Descriptionunclassified

“…Sa description précise est cruciale pour les calculs de dose. Elle fixe le mode de fonctionnement de l'accélérateur (Electron ou Photon) (Bramoullé, 2000 ;Douglas et al, 1990 ;Hedtjarn et al, 2000 ;Hokkanen et al, 1997 ;Jan et al, 2004 ;Lazaro, 2003 ;Maigne, 2005 ;Maigne et al, 2004 ;Masurier, 1999) et permet de contrôler les caractéristiques du faisceau (dimension, intensité, …). La modélisation de cette partie de l'accélérateur par GATE est effectuée précisément suivant les données du constructeur.…”

Section: Simulation Des Faisceaux D'électrons Utilisés En Radiothérapieunclassified

Simulation Monte Carlo des dépôts de doses en radiothérapie curiethérapie et déploiement sur grille de calcul

et al. 2007

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RÉSUMÉ ABSTRACT Monte Carlo simulation of doses deposits for radiotherapy -brachytherapy and deployment on the computing grid.Monte Carlo is the algorithm that most closely models the actual physics of the energy deposition process. Thus it would be very interesting to use this method in the cancer treatment planning by radiation. Indeed, existing treatment planning systems (TPS) are limited in the accuracy of dose calculations for certain specific cases. In this approach, we are interested in the validation GATE Monte Carlo toolkit for dosimetric applications in medical physics (Radiotherapy and Brachytherapy). However, the use of Monte Carlo method for complex geometries or images with a large resolution requires a large computing time. Indeed, a precise result can be obtained only by generating a large number of events. We thus study the performances of the computing grid to reduce computing time by deploying GATE simulations on the grid architecture developed within the framework of EGEE European project.

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Theoretical calculations of dose distributions for beta‐ray eye applicators

Cited by 25 publications

References 11 publications

Monte Carlo Estimation of Absorbed Dose Distributions Obtained from Heterogeneous 106Ru Eye Plaques

Monte Carlo Estimation of Absorbed Dose Distributions Obtained from Heterogeneous 106Ru Eye Plaques

Stellungnahme der Retinologischen Gesellschaft, der Deutschen Ophthalmologischen Gesellschaft und des Berufsverbands der Augenärzte Deutschlands zur Strahlentherapie bei neovaskulärer altersabhängiger Makuladegeneration

Simulation Monte Carlo des dépôts de doses en radiothérapie curiethérapie et déploiement sur grille de calcul

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