Theoretical and Experimental: The Synthetic and Anion-Binding Properties of Tripodal Salicylaldehyde Derivatives

Abstract

A series of colorimetric anion probes 1–6 containing OH and NO2 groups were synthesized, and their recognition properties toward various anions were investigated by visual observation, ultraviolet–visible spectroscopy, fluorescence, 1H nuclear magnetic resonance titration spectra and theoretical investigation. Nanomaterials of three compounds 2–4 were prepared successfully. Four compounds 3–6 that contain electron-withdrawing substituents showed a high binding ability for AcO−. The host–guest complex formed through a 1:1 binding ratio, and color changes were detectable during the recognition process. Theoretical investigation analysis revealed that an intramolecular hydrogen bond existed in the structures of compounds and the roles of molecular frontier orbitals in molecular interplay. These studies suggested that this series of compounds could be used as colorimetric probes to detect of AcO−.

The arginine detection and cytotoxicity of fluorescent probes based on naphthalene derivatives

“…In particular, biosensors, as tools for detecting amino acids, have gained more and more attentions . So, the detection of amino acids is very vital in organisms …”

Synthesis, binding ability, and cell cytotoxicity of fluorescent probes for l‐arginine detection based on naphthalene derivatives: Experiment and theory

“…Because of this, Arg can be discovered in especially high concentrations in seedlings and reserve organs. l ‐Arginine is glucogenic and half‐essential for humans and is an important metabolite of the urea cycle and also used as a drug in clinical therapy of endocrine diseases and hyperammonemia . In addition, Arg plays important roles in cell division, the healing of wounds, the removal of ammonia from the body, the function of the immune system, the releasing of hormones, and in particular, gene regulation, glycoprotein targeting, and vesicle transport .…”