Theobroma cacao fortified-feed ameliorates potassium bromate-induced oxidative damage in male Wistar rat

Nwonuma, Charles Obiora; Abdurrahman, Jadesola Edna; Rotimi, Damilare; Evbuomwan, Ikponmwosa Owen; Lele, Kelechi Charity; Alejolowo, Omokolade Oluwaseyi; Ezea, Samson Chukwuemeka; Asogwa, Nnaemeka; Oludipe, Emmanuel O

doi:10.1016/j.toxrep.2023.02.007

Cited by 2 publications

(2 citation statements)

References 49 publications

(48 reference statements)

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“…According to these data, the results in agreement with [29] who demonstrated that exposure rats to KBrO3 retards their growth and stimulate decreasing organ weight. In addition, these outcomes in agreement with [30] who revealed that KBrO 3 induced oxidative damage, apoptosis and reduced body and organ weight significantly in rats.…”

Section: Related Testes Organ Weightsupporting

confidence: 90%

Testicular Tissue Injury and Sperms Abnormalities Induced by Potassium Bromate and the Ameliorative Effect of Sesame Oil in Male Rats

Ali Jasim

2024

IOP Conf. Ser.: Earth Environ. Sci.

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The potassium bromate is one of the food additives, mostly it used in bakeries as flour improver and dough conditioner. It is a nephrotoxic in humans and probable carcinogenic in human and rats. Depending on its duration of exposure and dose, it employs a various degree of toxicity consumed with food and water in the many organisms. The study was conducted to investigate about harmful and toxic effects of potassium bromate in addition, the protective role of sesame oil in male rats. The criteria for assessment measured through sperms head and tail abnormality rate, histopathological, and relative testes organ weight. Thirty-two male rats (Rattus norvegicus) were used, the animals were separated in to four groups; each group consisted of eight animals. The first group treated distilled water considered a control, second group treated by sesame oil (4 ml/kilogram of body weight), the third group received about (12 mg of potassium bromate per one kilogram of body weight) and the fourth group received potassium bromate and sesame oil for 21 days. This study indicated significant increment p≤0.05 in the rate of sperm head and tail abnormality in group treated with potassium bromate and group treated with potassium bromate plus sesame oil as comparison with controls. In addition, the results identified significant decrement p≤0.05 of sperm head and tail abnormality rate in animal group treated with potassium bromate plus sesame oil when they were compared with group treated by potassium bromate alone. Additionally, the research identified damages in testes tissues of potassium bromate treated group and potassium bromate plus sesame oil group compared with controls. The study also indicated slightly histopathological damages in testes tissue in group was administrated potassium bromate plus sesame oil compared with group which was administrated potassium bromate only. The results reported significant decrement p≤0.05 of relative testes weight in animal group that was treated by potassium bromate, potassium bromate plus sesame oil compared by controls. Additionally, the results showed the positive role of sesame oil in significantly p≤0.05 enhancing KBrO3 affecting relative testes weight.

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Section: Related Testes Organ Weightsupporting

confidence: 90%

Testicular Tissue Injury and Sperms Abnormalities Induced by Potassium Bromate and the Ameliorative Effect of Sesame Oil in Male Rats

Ali Jasim

2024

IOP Conf. Ser.: Earth Environ. Sci.

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“…Mez (= Mespilodaphne sassafras Meisn.) canela-sassafrás, sassafrás essence 105, 108 Root Native c Aromatic root used in therapy (undefined) and essences Antifungal [ 90 ]; anticoagulant [ 91 ] Lecythidaceae Lecythis ollaria L. sapucaia, camari-macaco 85,103 Almonds Exotic Food and medicinal (undefined) Wound healing [ 92 ]; Selenium poisoning (e.g., alopecia) [ 93 , 94 ] Loganiaceae Spigelia anthelmia L. not mentioned 104 Not mentioned Native Poisonous when fresh and vermifuge when dry Anthelmintic † [ 95 , 96 ]; cardiac contraction [ 97 , 98 ]; neuromuscular blockade [ 99 ] Malvaceae Theobroma cacao L. cacaueiro 103 Cacao butter Native Medicinal (undefined) Antioxidant [ 100 , 101 ]; anti-inflammatory [ 102 ]; neuroprotective [ 103 ]; cardioprotective, hepatoprotective and nephroprotective combined with doxorubicin [ 104 ]; antialopecia [ 105 ] Meliaceae Carapa procera DC. (= Carapa guyanensis Oliv.)…”

Section: Resultsmentioning

confidence: 99%

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

Silva,

Oliveira,

Baratto

2024

J Ethnobiology Ethnomedicine

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Background Frederico José de Santa-Anna Nery (1848–1901) was a Brazilian Baron who referred to himself as a "volunteer propagandist" for Brazil in Europe, serving as an immigration agent to publicize the living conditions in the Amazon region, advocating for its development and modernization at the end of the nineteenth century. Santa-Anna Nery’s most famous book is "Le Pays des Amazones" (The Lands of the Amazons), first published in 1885, which the author dedicated a chapter to introduce and report on the Amazonian useful plant species and its relationship with humans. The aim of this work is to understand the historical context and ethnobotanical value of the plant species in the Brazilian Amazon at the end of the nineteenth century through an analysis of the book “Le Pays des Amazones” (1885) by Baron de Santa-Anna Nery, as well as to bring to light the historical importance of this very influential propagandist, who has been forgotten nowadays. Methods The original book “Le Pays des Amazones” (1885), as well as the original 3rd edition and its translated version into Portuguese, was carefully analyzed and all information about plants was systematized, with botanical names being updated. Finally, using the scientific name of medicinal plants alone or in combination with their traditional use, a search was carried out in databases in order to indicate current pharmacological studies that provide evidence about the described traditional uses. Results A total of 156 plant species were identified in the book, although 132 species had their scientific names updated. These species belong to 45 different families, with Fabaceae and Arecaceae the most represented, and 109 plants are Brazilian native. Considering only the 36 medicinal plants, the main medicinal indications reported were astringent, purgative/laxative, stimulant and tonic, vermifuge, febrifuge, sudorific, emetic, diuretic and antidysenteric. Regarding other useful plants (non-medicinal), 97 species were cited for food, constructions and buildings, spices and condiments, ornaments and objects, carpentry, textile fibers, gums, oils, balms and essences, pigments and tanning, hunting and fishing. Conclusions When the book “Le Pays des Amazones” is analyzed from a timeless perspective, with a particular focus on historical ethnobotany, it is possible to observe the economic, social, and political importance of many useful plants for the Amazon at the end of the nineteenth century and how the relationship between local people, indigenous communities, and immigrants was established with plant biodiversity.

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Theobroma cacao fortified-feed ameliorates potassium bromate-induced oxidative damage in male Wistar rat

Cited by 2 publications

References 49 publications

Testicular Tissue Injury and Sperms Abnormalities Induced by Potassium Bromate and the Ameliorative Effect of Sesame Oil in Male Rats

Testicular Tissue Injury and Sperms Abnormalities Induced by Potassium Bromate and the Ameliorative Effect of Sesame Oil in Male Rats

Amazonian useful plants described in the book “Le Pays des Amazones” (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective

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