Thelarche, Pubarche, and Menarche Attainment in Children With Normal and Elevated Body Mass Index

Rosenfield, Robert L.; Lipton, Rebecca B.; Drum, Melinda L.

doi:10.1542/peds.2008-0146

Cited by 410 publications

(234 citation statements)

References 21 publications

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“…Because data are conflicting on the effect of obesity on boys' puberty, 9,[18][19][20] we examined relationships between BMI and ages of onset of sexual maturity stages. Pooling race/ethnicity (because of small sample size) and controlling for age, boys with BMI ,15th percentile had later mean ages of transition to stages 2 to 4 for genital and pubic hair growth than boys with BMI .85th percentile (data not shown).…”

Section: Figurementioning

confidence: 99%

Secondary Sexual Characteristics in Boys: Data From the Pediatric Research in Office Settings Network

et al. 2012

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WHAT'S KNOWN ON THIS SUBJECT: Recent investigations of pubertal onset in US girls suggest earlier maturation. The situation for US boys is unknown, and existing investigations are outdated and lack information on a key physical marker of male puberty: testicular enlargement.WHAT THIS STUDY ADDS: US boys appear to be developing secondary sexual characteristics and achieving testicular enlargement 6 months to 2 years earlier than commonly used norms, with African American boys entering Tanner stages 2 to 4 earlier than white or Hispanic boys. abstract BACKGROUND: Data from racially and ethnically diverse US boys are needed to determine ages of onset of secondary sexual characteristics and examine secular trends. Current international studies suggest earlier puberty in boys than previous studies, following recent trend in girls. METHODS:Two hundred and twelve practitioners collected Tanner stage and testicular volume data on 4131 boys seen for well-child care in 144 pediatric offices across the United States. Data were analyzed for prevalence and mean ages of onset of sexual maturity markers. RESULTS:Mean ages for onset of Tanner 2 genital development for nonHispanic white, African American, and Hispanic boys were 10.14, 9.14, and 10.04 years and for stage 2 pubic hair, 11.47, 10.25, and 11.43 years respectively. Mean years for achieving testicular volumes of $3 mL were 9.95 for white, 9.71 for African American, and 9.63 for Hispanic boys; and for $4 mL were 11.46, 11.75, and 11.29 respectively. African American boys showed earlier (P , .0001) mean ages for stage 2 to 4 genital development and stage 2 to 4 pubic hair than white and Hispanic boys. No statistical differences were observed between white and Hispanic boys.CONCLUSIONS: Observed mean ages of beginning genital and pubic hair growth and early testicular volumes were 6 months to 2 years earlier than in past studies, depending on the characteristic and race/ ethnicity. The causes and public health implications of this apparent shift in US boys to a lower age of onset for the development of secondary sexual characteristics in US boys needs further exploration.

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Section: Figurementioning

confidence: 99%

Secondary Sexual Characteristics in Boys: Data From the Pediatric Research in Office Settings Network

et al. 2012

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“…Age at menarche is determined by multiple factors such as nutritional status, ethnic or racial background, birth weight, and mother's age at menarche, among others 1,2,3,4 .…”

Section: Introductionmentioning

confidence: 99%

Socioeconomic status and age at menarche in indigenous and non-indigenous Chilean adolescents

et al. 2012

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“…Factors regulating AAM are not well understood, but in developed countries, about one-half of the variation in AAM is thought to be genetic. 1,2 Other mediating factors include birth and childhood body size, [3][4][5][6] adiposity, 3,7 growth, [8][9][10] race/ethnicity, [11][12][13] socioeconomic position, [13][14][15][16][17] family relationships and structure, 11,16,18,19 and exposure to childhood adversity and trauma. 20,21 Younger AAM has widely been proposed as a risk factor for early first sexual intercourse (FSI).…”

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confidence: 99%

Age at Menarche and Age at First Sexual Intercourse: A Prospective Cohort Study

et al. 2013

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WHAT'S KNOWN ON THIS SUBJECT: Young age at first sexual intercourse (FSI) is related to risk-taking behaviors and negative outcomes. Previous studies using a cohort or cross-sectional design have concluded that younger age at menarche (AAM) is related to younger age at FSI. WHAT THIS STUDY ADDS:This large birth cohort study is the first to address the temporal relationship between AAM and FSI. We found that younger AAM does not confer higher risk of early FSI, whether in terms of calendar age or time since menarche. abstract OBJECTIVE: Younger age at menarche (AAM) may put girls at risk for earlier first sexual intercourse (FSI). Young age at FSI has far-reaching negative outcomes. We describe the longitudinal relationship between AAM and FSI in a large prospective birth cohort.METHODS: AAM was collected from 554 girls from the Western Australia (Raine) Pregnancy Cohort Study, prospectively from age 10 or retrospectively at age 14. Age at FSI was collected at ages 17 and 20. Cox regression models describe likelihood of FSI by age and years since menarche for younger (,12 years) and older ($14 years) AAM relative to average AAM (12-13 years). RESULTS: CONCLUSIONS:Younger AAM was not a risk factor for younger age at FSI in this cohort.

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Thelarche, Pubarche, and Menarche Attainment in Children With Normal and Elevated Body Mass Index

Cited by 410 publications

References 21 publications

Secondary Sexual Characteristics in Boys: Data From the Pediatric Research in Office Settings Network

Secondary Sexual Characteristics in Boys: Data From the Pediatric Research in Office Settings Network

Socioeconomic status and age at menarche in indigenous and non-indigenous Chilean adolescents

Age at Menarche and Age at First Sexual Intercourse: A Prospective Cohort Study

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