Theeffect of Doxorubicin and Thioridazine on Squamous Carcinoma Cell Line

doi:10.21608/asdj.2020.164446

Cited by 1 publication

(1 citation statement)

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“…11 Recently, there are interesting treatment strategies that use phytochemicals in order to reduce its side effects and normal cell toxicity. [12][13][14] Thymoquinone (TQ) showed an increased range of pharmacological properties including antimicrobial, analgesic, anti-inflammatory, antihypertensive, anticarcinogenic, histamine release inhibitor, antioxidant, hypoglycemic, and hepatoprotective properties. 12 Moreover, TQ has been reported as one of those phytochemicals that showed promising results in cancer management.…”

Section: Introductionmentioning

confidence: 99%

Potential Effect of Thymoquinone on HNO-97 Cell Line

Eloraby,

Elgayar,

Mokbel

et al. 2024

Ain Shams Dental Journal

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Aim: the aim of this the study was to evaluate the histopathological changes of the buccal mucosa in the advanced age of albino rats and linking these changes with increased tissue cancer tendency. Materials and methods: fourteen adult male albino rats were randomly divided into two equal groups as follow: Group 1: 6 months old group. Group 2: 24 months old group. all animals were euthanized and buccal mucosa specimen were processed for hematoxylin and eosin staining and immunohistochemically prepared for e-cadherin gene expression. Results: histological examination of buccal mucosal tissues (epithelium and lamina propria) of group 2 showed significant atrophic changes and sort of loss of the tissue integrity as compared to group I. Significant downregulation of e -cadherin gene expression was also noticed in the aged group. Conclusion: the present study concluded that oral tissues demonstrate progressive decline in their functional properties as a result of changes related to aging.

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