The η⁴-Dienyl Tricarbonyliron Moiety in Heterocyclic Synthesis. A Rare 1,2-Migration of the Complexation Site as a Key Step for a Novel Stereoselective Preparation of trans-2,3-Disubstituted 1,4-Dioxanes

Heterocycles via intramolecular platinum-catalyzed propargylic substitution

“…21 As their utility in a number of applications continues to be investigated, for example, in use as photoreceptors, 22 in perfumes, 23 and as anti-tumoral 24 and anti-viral agents, 25 there remains a pressing need for additional methods for their preparation. A simple derivation of the original substrates by inclusion of an oxygen atom in the tether was envisaged to allow access to 1,4-dioxanes of varying substitution patterns.…”

Stoichiometric Applications of Acyclic π-Organoiron Complexes to Organic Synthesis

“…The reaction of transoid (pentadienyl)iron cations, generated via ionization of (dienyl the intermediacy of transoid pentadienyl cations has been reported to afford dienyl-fluorides 88 in a stereoselective fashion [91]. Cyclization of dienols 87, bearing a pendant heteroatom nucleophile, under acidic conditions affords 5, 6, or 8-membered ring dienyl hetero-cycles 89 and 90…”

Utility of a diene–tricarbonyliron complex as mobile chiral auxiliary: iterative use for constructing contiguous chiral centers

“…Thus far, several efficient methods, which skip the isolation of the acyclic (pentadienyl)iron(1+) cations (in situ generation), have been developed and applied to natural product synthesis. 4 Previously, we described the regio-and stereo-selective 1,5-nucleophilic substitution of the cyanophosphate Fe(CO) 3 complexes with several heteroatomic nucleophiles, giving the 1,2-migrated products of the Fe(CO) 3 group with (E,Z)configuration. 5 Here, we wish to describe the regio-and stereoselective synthesis of (E,E)-1,5-substituted adducts and their novel application to construction of contiguous stereogenic centers in acyclic alkenes (Scheme 1).…”