The zoonosis sporotrichosis can be successfully treated by photodynamic therapy: A scoping review

Legabão, Bárbara Cipulo; Fernandes, Juliana Aparecida; Barbosa, Gabriela Franco de Oliveira; Mendonca, Patricia; Svidzinski, Terezinha Inez Estivalet

doi:10.1016/j.actatropica.2022.106341

Cited by 9 publications

(7 citation statements)

References 64 publications

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“…Local hyperthermia and cryosurgery are safe and efficacy options for treating pregnant women with cutaneous sporotrichosis [ 275 , 276 ]. Photodynamic therapy could also be applied as a non-pharmacological treatment for sporotrichosis, considering the promising in vitro and in vivo studies; however, further clinical observation is still necessary [ 277 ].…”

Section: Trends In the Treatment Of Sporotrichosismentioning

confidence: 99%

Current Progress on Epidemiology, Diagnosis, and Treatment of Sporotrichosis and Their Future Trends

Rodrigues

Gonçalves

Carvalho

et al. 2022

JoF

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Sporotrichosis, a human and animal disease caused by Sporothrix species, is the most important implantation mycosis worldwide. Sporothrix taxonomy has improved in recent years, allowing important advances in diagnosis, epidemiology, and treatment. Molecular epidemiology reveals that S. brasiliensis remains highly prevalent during the cat-transmitted sporotrichosis outbreaks in South America and that the spread of S. brasiliensis occurs through founder effects. Sporothrix globosa and S. schenckii are cosmopolitan on the move, causing major sapronoses in Asia and the Americas, respectively. In this emerging scenario, one-health approaches are required to develop a creative, effective, and sustainable response to tackle the spread of sporotrichosis. In the 21st century, it has become vital to speciate Sporothrix, and PCR is the main pillar of molecular diagnosis, aiming at the detection of the pathogen DNA from clinical samples through multiplex assays, whose sensitivity reaches remarkably three copies of the target. The treatment of sporotrichosis can be challenging, especially after the emergence of resistance to azoles and polyenes. Alternative drugs arising from discoveries or repositioning have entered the radar of basic research over the last decade and point to several molecules with antifungal potential, especially the hydrazone derivatives with great in vitro and in vivo activities. There are many promising developments for the near future, and in this review, we discuss how these trends can be applied to the Sporothrix-sporotrichosis system to mitigate the advance of an emerging and re-emerging disease.

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Section: Trends In the Treatment Of Sporotrichosismentioning

confidence: 99%

Current Progress on Epidemiology, Diagnosis, and Treatment of Sporotrichosis and Their Future Trends

Rodrigues

Gonçalves

Carvalho

et al. 2022

JoF

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“…The obtained results were successful. More recently, in 2022, Legabão conducted an overview of in vitro and in vivo studies on PDT, investigating the photo-inactivation of the complex species of Sporothrix [ 18 ]. The results showed promising prospects in both humans and animals.…”

Section: Discussionmentioning

confidence: 99%

“…These tests demonstrated fungicidal effects, leading to the conclusion that photodynamic therapy holds significant potential in treating sporotrichosis. This study used methylene blue, with good results [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Beyond conventional approaches: Enhancing photodynamic therapy for refractory feline sporotrichosis caused by Sporothrix brasiliensis

Mesquita Ramos,

de Souza Rabello,

Ribeiro da Silva

et al. 2024

Medical Mycology Case Reports

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“…According to the PDT clinical guidelines, it is known that PDT is currently recommended for the treatment of AK, AC, BCC, Bowen's disease, moderate to severe and severe acne, rosacea, and photodamage, 23,31–33 etc. There are also numerous reports in the literature on the efficacy of PDT in some bacterial infections skin diseases, fungal infections skin diseases, viral infectious skin diseases, scar, skin amyloidosis, extramammary Paget Disease , 34–39 etc. In the future, we will try to apply PDT to more refractory diseases and work towards writing more complete clinical guidelines.…”

Section: Discussionmentioning

confidence: 99%

Trends in photodynamic therapy for dermatology in recent 20 years: A scientometric review based on CiteSpace

Huang,

Fu,

Tang

et al. 2023

J of Cosmetic Dermatology

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ObjectiveAnalyze the research state and development trend of photodynamic therapy for dermatology using visual knowledge graphs derived from the Web of Science Core Collection database.MethodsThe Web of Science Core Collection database was utilized as the search data source for the bibliometric analysis, and the associated articles published between January 1, 2000, and December 31, 2022, were obtained using the search terms “photodynamic therapy” and “dermatology”. CiteSpace, VOSviewer, and additional tools were utilized for bibliometric analysis, and visual knowledge graphs were created.ResultsEight hundred and thirty two articles were retrieved in total, and 747 were included following de‐duplication and transformation. The country with the greatest number of publications is the United States; the primary research institution was University of Copenhagen; and the references with the highest centrality were primarily concerned with the selection of photosensitizers; High frequency keywords primarily comprised 5 aminolevulinic acid and basal cell carcinoma; and the clustering graph revealed that all keywords fell into 11 categories.ConclusionIn numerous areas of dermatology, photodynamic treatment is commonly employed. Current research focuses on nonneoplastic skin diseases and the choice of photosensitizers. Nonetheless, its specific mechanism and other applications merit further investigation.

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The zoonosis sporotrichosis can be successfully treated by photodynamic therapy: A scoping review

Cited by 9 publications

References 64 publications

Current Progress on Epidemiology, Diagnosis, and Treatment of Sporotrichosis and Their Future Trends

Current Progress on Epidemiology, Diagnosis, and Treatment of Sporotrichosis and Their Future Trends

Beyond conventional approaches: Enhancing photodynamic therapy for refractory feline sporotrichosis caused by Sporothrix brasiliensis

Trends in photodynamic therapy for dermatology in recent 20 years: A scientometric review based on CiteSpace

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