We study the properties of some distinguished subspaces of the Zariski space Zar(K|D) of a field F over a domain D, in particular the topological properties of subspaces defined through algebraic means. We are mainly interested in two classes of problems: understanding when spaces of the form Zar(K|D) \ {V } are compact (which is strongly linked to the problem of determining when Zar(K|D) is a Noetherian space), and studying spaces of rings defined through pseudo-convergent sequences on an (arbitrary, but fixed) rank one valuation domain.