The Z‐plasty contributes to the coalescence of a chronic non‐healing wound

Abstract

This study aimed to explore the treatment effect of Z-plasty on a non-healing wound. A total of 72 patients diagnosed with a chronic non-healing wound in Peking University Third Hospital from November 2009 to August 2019 were retrospectively analysed. Among them, 27 patients were treated with Z-plasty, and 45 patients were treated with the general method. Detailed patient information was retrieved from medical records, including age, gender, body mass index (BMI), alcohol, smoking, and comorbidities (diabetes mellitus, hypertension, heart disease). Surgical parameters included operation time and intraoperative blood loss. Wound swelling, epidermal blisters, wound edge colour, and skin temperature at 1 day after surgery were assessed to evaluate the blood supply of the wound. Surgical complications included infection, haematoma, dehiscence, and non-healing within 2 weeks postoperatively. Student t test (for continuous data) and Chi-square test (for categorical data) were conducted to determine the statistical difference. We found no significant differences in age, gender, BMI, alcohol, smoking, and comorbidities between the two groups. Z-plasty did not show any advantages in the surgical time, invasive blood loss, hospital days, and hospitalisation expenses. The incidence of abnormal wound edge colour with Zplasty was significantly lower than that with the general treatment (P < .05), and the Z-plasty enables better healing of the patient's wound (P < .05). Z-plasty promoted better recovery of chronic non-healing wounds than direct suturing.

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“…(c) The wound was soaked in 2.5% iodophor solution for 10 to 15 minutes. 18 (d) Determine the specific wound closure operation according to the condition of the wound.…”

“…(b) A 50 mL syringe with a needle was used to compress the gap between the internal fixator and the tissue, and a large amount of normal saline, 3% hydrogen peroxide and 2.5% iodophor were used to repeatedly rinse and scrape the wound to remove the necrotic or infected tissue. (c) The wound was soaked in 2.5% iodophor solution for 10 to 15 minutes 18 . (d) Determine the specific wound closure operation according to the condition of the wound.…”

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“…Similarly, obesity can contribute to increased pressure on the lower extremities, predisposing individuals to the development of pressure ulcers [ 9 ]. Heart disease and its associated risk factors, such as dyslipidemia and hypertension, might be linked to impaired wound healing due to their effects on vascular health and inflammation [ 10 ]. Hypercholesterolemia, characterized by high levels of cholesterol in the blood, has been identified as a factor that can influence wound healing processes.…”