The yerba mate intake has a neutral effect on bone: A case–control study in postmenopausal women

Abstract

Nutritional factors have been associated with osteoporosis and fractures. The intake of coffee may increase the risk of fracture whereas the intake of black and green tea is associated with its reduction. Recently, consumption of yerba mate was associated with increased bone mineral density in postmenopausal women. Nonetheless, its influence on fracture is not known. The aim of this study was to evaluate the effect of yerba mate tea intake on fractures, bone markers, calcium homeostasis, and oxidative stress in postmenopausal women. A case-control study was carried out in South Brazil, 46 women with fractures and 49 controls completed the study. There was no significant difference between the frequency of fractures in women who drank mate tea and women who did not (48.3% vs. 48.5%, p = .99). Moreover, there was no significant difference concerning the serum levels of total calcium, phosphorus, PTH, vitamin D, P1NP, and CTX in the subjects with the history of yerba mate use when compared to controls. Higher serum levels of NOx were found in women who drank the yerba mate infusion. In conclusion, the yerba mate intake is not associated with fracture, and it appears to have a neutral effect on the bone metabolism.

Protective effect of yerba mate intake on the cardiovascular system: a post hoc analysis study in postmenopausal women

“…The characteristics of the original cohort and the case-control study are described in detail elsewhere ( 7 , 8 ). Table 1 shows the clinical characteristics of the participants with a daily consumption of mate.…”

“…This study was a post hoc analysis of the case-control study ( 7 ) nested in the Obesity and Bone Fracture Cohort ( 8 ) that aimed to evaluate the association between bone fracture and the intake of the aqueous extract of mate tea consumed as “ chimarrão ” in postmenopausal women. It was conducted in the municipality of Santa Maria, RS, Brazil.…”

“…Women at menacme and those with cognitive deficits or communication difficulties were excluded from the survey. All 46 women with confirmed major bone fractures in the original cohort and 49 randomly selected controls without fractures ( 7 ) were included in this post hoc analysis (n=95).…”

Causal Effects of Tea Intake on Multiple Types of Fractures: A Two-Sample Mendelian Randomization Study

“…Veiga et al studied the fracture risk of yerba mate intake in 95 postmenopausal women in southern Brazil. They found that yerba mate intake had no effect on fracture but affected bone metabolism [10]. Dai et al found no relationship between tea intake and hip fractures in a prospective cohort of 63,257 Singaporean-based people aged 45 to 74 [25].…”

“…It is reported that tea drinking has particular benefits in reducing the risk of osteoporosis [7], primary prevention of cardiovascular diseases [8], and blood glucose control [9]. Previous studies have investigated the relationship between tea consumption and fracture risk [10][11][12][13], but the results are not inconsistent.…”