"The Yellow IRIS" urinalysis workstation--the first commercial application of "automated intelligent microscopy".

Abstract

Since 1982, "automated intelligence microscopy" (AIM) has been refined and adapted to perform the portion of the urinalysis profile traditionally done by a microscope. AIM and analytical subsystems measuring relative density and performing dipstick chemistry compose the main elements of "The Yellow IRIS" urinalysis workstation, an attended system for automation and standardization of routine urinalysis. Performance data gathered at three laboratory test sites show AIM to be analytically consistent over the required range of particulate enumeration, and show that it detects 20% more abnormalities than by conventional microscopy, and with greater precision (CVs 5 to 20%). Complete urinalysis, including the microscopic examination, requires little more than 1 min for normal specimens, 3 min for most abnormal specimens. Actual throughput rate varies with the particulate composition of specimens; typically, it averages greater than 30 specimens per hour, a 300% improvement in urinalysis productivity by CAP standards and an almost 500% improvement when typical emergency-use demands are taken into account.

Clinical laboratory automated urinalysis: comparison among automated microscopy, flow cytometry, two test strips analyzers, and manual microscopic examination of the urine sediments

“…Although there is no established reference method for urinalysis, the manual analysis of urine sediment continues to be considered as the suitable method for routine laboratories (10). Nevertheless, it is fraught with methodological problems, which generate high imprecision when compared with automated methods (5). A substantial amount of different factors may contribute to the imprecision in manual urinalysis (3).…”

Comparison of IRIS Iq200, UF-1000i, and Cobas u701 Module Automated Urine Sediment Analyzers

“…Although the manual standardized microscopic sediment test has been acknowledged as a reference method [5,6], it is time consuming, labor intensive, and shows poor reproducibility due to IRIS Iq200, UF-1000i, Cobas u701 자동요침사분석장비의 비교 평가 the interpretation pro ciency of technicians [7][8][9]. For this reason, automated urine sediment analyzers have begun to emerge to overcome longstanding issues [4,[10][11][12], and they have now become a necessity in tertiary hospitals, in Korea. This automated testing system has reduced the labor and time required, enabling laboratories to handle many more tests and to reduce the turnaround time, while also improving precision [13,14].…”

UriSed 3 and UX‐2000 automated urine sediment analyzers vs manual microscopic method: A comparative performance analysis

“…Many studies have compared the performance of automated urine sediment analyzers against each other and against manual sediment microscopy. 1,[6][7][8][9][10][11] In 2009, a Hungarian company named 77 Elektronika Kft. developed and introduced a new automated urine sediment analyzer and marketed it under the names UriSed or sediMAX in some countries.…”