The wound healing properties of Channa striatus-cetrimide cream — tensile strength measurement

Baie, Saringat; Sheikh, K.A

doi:10.1016/s0378-8741(99)00184-1

Cited by 80 publications

(75 citation statements)

References 7 publications

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“…Hexosamine and uronic acid are matrix molecules that act as ground substratum for the synthesis of the new extracellular matrix. The decrease in hexosamine and uronic acid content was associated with concomitant increase in collagen content [39]. Uronic acid in the wound attracts fibroblast and stimulates collagen synthesis by providing more fluid that facilitates greater cell mobility, early remodeling, and helps the wound to heal without scar formation [40,41].…”

Section: Discussionmentioning

confidence: 99%

Triphala Promotes Healing of Infected Full-Thickness Dermal Wound

Muthusamy

Shanmugam

Sripriya

et al. 2008

Journal of Surgical Research

121

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Section: Discussionmentioning

confidence: 99%

Triphala Promotes Healing of Infected Full-Thickness Dermal Wound

Muthusamy

Shanmugam

Sripriya

et al. 2008

Journal of Surgical Research

121

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“…The wound tensile strength was determined in all groups on the twentieth day by texture analyzer (TA XT2). 20 Rats were lightly anesthetized with ether. The skin was removed with one cm on each side of the wound.…”

Section: Tensile Strengthmentioning

confidence: 99%

Untitled

2016

IJPSR

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ABSTRACT:Mentha piperitais currently one of the most economically important aromatic and medicinal crops in all over the world. Phytochemical investigation of the leaves of Mentha piperita (L.) (Lamiaceae) yielded a new compound, which is decarboxyrosemarinic acid galactoside. Formulate as 3', 4'-dihydroxy-β-phenyl ethyl caffeate-4-(3'''-menthyl)-4'-β-D-galacto pyranoside. 13C NMR, 1H NMR, FABMS, IR were used for structural characterization. Wound healing responses of this compound was evaluated from biochemical as well as biophysical parameters and analyze the role of isolated compound. The parameters studied included rate of wound contraction and the period of epithelialization in excision wound model. Tissues were removed on different days of intervals and subsequently analyzed for specific assays Tensile strength in incision wound model was assessed along with histopathological examinations. Compound-1was found to increase the cellular proliferation and collagensynthesis at the wound site, as indicated by increases in amounts of DNA synthesized, protein content. Compound-1treatment was also shown to decrease the levels of lipid peroxides (LPs), while the activity of enzymes superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), were significantly found to be increased when compared to the control. This study demonstrates and validates the efficacy of Mentha piperita isolated compounds on wound healing activity.

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“…Rats were fed with regular chow feed and free access of water and rats were sacrificed on the 7th post-wounding day because preliminary experiments had shown this to be a good time to detect any increase in tensile strength from drug treatment (Fenton and West, 1963;Chitra et al, 1998) Tensile strength was measured using a texture analyzer and the increase in tensile strength served as a measure of wound healing (Baie et al, 2000).…”

Section: Incision Woundsmentioning

confidence: 99%