The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease

Seckeler, Michael D.; Hoke, Tracey R.

doi:10.2147/clep.s12977

Cited by 381 publications

(344 citation statements)

References 171 publications

(126 reference statements)

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“…10,11,13,27,28 Compared to HICs however, these findings are remarkable in that RHD is identified in only 3% of IE cases. 1 This is likely because the prevalence of RHD is disproportionately high in LMICs, 29,30 which bear 79% of the global RHD burden. 15 Underlying CHD accounts for 5-23% of reported IE cases.…”

Section: Underlying Cardiac Conditionsmentioning

confidence: 99%

Infective Endocarditis in Low- and Middle-Income Countries

et al. 2017

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Key Points Staphylococcus is an increasingly important cause of IE in LMICs, and is the leading cause of IE in UMICs  RHD remains the major underlying cardiac pathology of IE in LMICs, identified in almost half of reported cases  The rate of microorganism non-identification is high, reaching up to 60% of IE cases in LMICs, and hampering diagnosis and treatment  Rates of access to surgery in UMICs for complicated IE are as high as in HICs, but remain dismal in lower-middle income countries SynopsisInfective endocarditis (IE) is a rare, life-threatening disease with a mortality rate of upto 25% and significant debilitating morbidities. Although much has been reported on contemporary IE in high income countries, conclusions on the state of IE in low and middle income countries (LMICs) are based on studies conducted before the year 2000. Furthermore, unique challenges in the diagnosis and management of IE persist in LMICs. This article is a review of IE studies conducted in LMICs documenting clinical experiences from the year 2000 to present. We present the causes of IE, management of patients with IE and the prevailing challenges in diagnosis and treatment of IE in LMICs.

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Section: Underlying Cardiac Conditionsmentioning

confidence: 99%

Infective Endocarditis in Low- and Middle-Income Countries

et al. 2017

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“…21 Our study included 74 (7.3%) patients of RHD with prevalence of AF of 70%. AF in RHD contributed to 37.14% of total AF burden in our study.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of Atrial Fibrillation in patients attending emergency department of Shahid Gangalal National Heart Centre, Kathmandu, Nepal

et al. 2016

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Background and Aims: Atrial fibrillation (AF) is the most common sustained arrhythmia. This study aims to evaluate its prevalence in patients attending emergency department of tertiary care cardiac centre.Methods: It was a prospective observational study of 1012 consecutive patients who attended emergency department of Shahid Gangalal National Heart Centre from September 2014 to November 2014. Electrocardiogram, demographic features, diagnosis and clinical presentations were reviewed.Results: Among the 1012 patients, 553 (54.6%) were male and 459(45.4%) were female. Mean age was 52.13} 17 years. A total of 140 patients (13.8%) patients had AF. The mean age of patients with AF was 55 years. The prevalence of AF was higher in female than male (19.2% Vs 9.4%). Among the Rheumatic heart disease patients, seventy percentages of them had AF. Dyspnea was the commonest symptom of patients with AF followed by palpitation.Conclusion: The prevalence of AF in our study is higher than in western world mainly because of endemic rheumatic heart disease.Nepalese Heart Journal 2016; 13(1): 1-4

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“…(2) The prevalence of chronic RHD, the legacy of ARF, continues to rise in all regions of the world, except Europe and parts of the Americas. (3) Atrial fibrillation (AF) is a major complication of chronic RHD. AF develops in approximately 18 -39% of RHD patients and increases the risk of thromboembolism.…”

Section: Introductionmentioning

confidence: 99%

Management of rheumatic atrial fibrillation

Chin

2017

SAHJ

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The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease

Cited by 381 publications

References 171 publications

Infective Endocarditis in Low- and Middle-Income Countries

Infective Endocarditis in Low- and Middle-Income Countries

Prevalence of Atrial Fibrillation in patients attending emergency department of Shahid Gangalal National Heart Centre, Kathmandu, Nepal

Management of rheumatic atrial fibrillation

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