The WHOHistological typing of odontogenic tumours. A commentary on the second edition

Abstract

This article introduces the revised World Health Organization (WHO) classification of odontogenic tumors and jaw cysts and certain bone lesions that either are peculiar to the jaws or have distinctive features in that location. The new and revised classification is compared with the previous version, the reasons for the changes are outlined, and reference is made to a number of newly characterized lesions that have been included.

Immunohistochemical expression of MMPs 1, 7, and 26 in syndrome and nonsyndrome odontogenic keratocysts

“…30 Type I collagen, responsible for connective tissue strength and rigidity, is the main bone organic matrix component 19 and MMP-1 is one of the proteases that can degrade the triple-helical domain of type I fibrillar collagen. [16][17][18] Fig.…”

“…In all cases, the histological diagnosis was based on the second WHO classification. 30 All the syndrome patients had been diagnosed according to the criteria proposed by Kimonis et al 31 and presented with multiple OKCs. The patients with sporadic OKCs had single lesions and had been clinically and radiographically assessed to exclude the presence of other Gorlin syndrome manifestations.…”

Odontogenic cysts: Demographic profile in a Brazilian population over a 38-year period

“…Thus, there is no race categorization that would reflect the true ethnic distribution. Hematoxylin/eosin-stained slides of OCs or nonspecific cyst diagnoses were selected and re-evaluated by three pathologists according to the 1992 World Health Organization (WHO) histologic classification (10). The histologic criteria for the diagnosis of calcifying odontogenic cysts were those proposed by Buchner (11).…”

Management and Treatment Outcomes of Maxillofacial Fibro-osseous Lesions: A Retrospective Study

“…Although the term fibro-osseous lesion had not been included in the WHO's classification of 1992 [4], these lesions were formally re-classified in 1993 [5] and have been included ever since, based on their biological behaviour and histopathology and in agreement with Waldron's recommendations of 1985. Thus FO lesions nowadays constitute a group of ''neoplasms and other tumours related to bone'' [5].…”