The website for a hospital museum: the Santa Maria Nuova case study

Landini, Giancarlo; Vannini, Ilaria Elisa; Giusti, Martina; Persiani, Niccolò

doi:10.1504/ijdcet.2020.10027411

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Beginning in 1849, Pacini held the Chair of General and Topographic Anatomy at the University of Florence. He performed autopsies, demonstrated microscopy techniques and engaged in other activities related to his professorship at Santa Maria Nuova Hospital in Florence [14].…”

Section: Background Of the Discovery Of V Choleraementioning

confidence: 99%

The enigma of Pacini’s Vibrio cholerae discovery

Carboni

2021

Journal of Medical Microbiology

View full text Add to dashboard Cite

During the 1854 cholera outbreak in Florence, Italy, Filippo Pacini documented that the cause of the infection was a bacterium. This conclusion was also independently reached by John Snow during the 1854 cholera outbreak in London. By using an epidemiological method, Snow found that the infection spread through a polluted water network. Snow identified a water pump as the source of the disease. After removing the infected handle of this pump, the cases of cholera rapidly began to decrease. A microscopic examination of the water showed organic impurities but no bacteria. This discovery was ignored during Snow’s lifetime. In contrast, through microscopy during the autopsies of cholera victims, Pacini observed that the disruption of their intestinal mucosa was closely associated with millions of the bacteria that he called Vibrio cholerae . Via histological techniques, Pacini detected that intestinal mucosa reabsorption dysfunction was the cause of debilitating diarrhoea, vomiting, severe dehydration and death. Nevertheless, his discovery of Vibrio cholerae was ignored during Pacini’s lifetime. A survey of Pacini’s autographic manuscripts suggests that Pacini and Snow may have shared mutual knowledge within their respective seminal papers. This survey also facilitates, for the first time, the creation of maps that illustrate the worldwide distribution of Pacini’s cholera papers from 1854 to 1881. The consistent neglect of Pacini’s discovery remains a true enigma.

show abstract

Section: Background Of the Discovery Of V Choleraementioning

confidence: 99%

The enigma of Pacini’s Vibrio cholerae discovery

Carboni

2021

Journal of Medical Microbiology

View full text Add to dashboard Cite

show abstract

The website for a hospital museum: the Santa Maria Nuova case study

Cited by 1 publication

References 0 publications

The enigma of Pacini’s Vibrio cholerae discovery

The enigma of Pacini’s Vibrio cholerae discovery

Contact Info

Product

Resources

About