The way to her heart? Response to romantic cues is dependent on hunger state and dieting history: An fMRI pilot study

Ely, Alice V.; Childress, Anna Rose; Jagannathan, Kanchana; Lowe, Michael R.

doi:10.1016/j.appet.2015.06.022

Cited by 3 publications

(2 citation statements)

References 60 publications

(81 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The information flow does not only involve reward pathways, such as the mesocorticolimbic system, but recruits coherent involvement of the visuospatial system increasing attention to smoking cues (Due et al, 2014). The connection between reward and visual networks (in relation to craving) increases the activation of relevant brain areas including the putamen and fusiform gyrus (Ely et al, 2015). In general, evidence from previous studies supports the existence of a relationship between dopaminergic and visuospatial functions in nicotine dependence.…”

Section: Discussionmentioning

confidence: 99%

The effect of preprocessing pipelines in subject classification and detection of abnormal resting state functional network connectivity using group ICA

et al. 2017

View full text Add to dashboard Cite

Resting state functional network connectivity (rsFNC) derived from functional magnetic resonance (fMRI) imaging is emerging as a possible biomarker to identify several brain disorders. Recently it has been pointed out that methods used to preprocess head motion variance might not fully remove all unwanted effects in the data. Proposed processing pipelines locate the treatment of head motion effects either close to the beginning or as one of the final steps. In this work, we assess several preprocessing pipelines applied in group independent component analysis (gICA) methods to study the rsFNC of the brain. The evaluation method utilizes patient/control classification performance based on linear support vector machines and leave-one-out cross validation. In addition, we explored group tests and correlation with severity measures in the patient population. We also tested the effect of removing high frequencies via filtering. Two real data cohorts were used: one consisting of 48 mTBI and one composed of 21 smokers, both with their corresponding matched controls. A simulation procedure was designed to test the classification power of each pipeline. Results show that data preprocessing can change the classification performance. In real data, regressing motion variance before gICA produced clearer group differences and stronger correlation with nicotine dependence.

show abstract

Section: Discussionmentioning

confidence: 99%

The effect of preprocessing pipelines in subject classification and detection of abnormal resting state functional network connectivity using group ICA

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Further, reduced activation in inferior, middle, and superior frontal gyri in response to monetary reward‐based decision making has been shown to predict weight gain in participants with obesity . Individuals prone to weight gain have also been shown to have differential neural responses to nonfood stimuli, suggesting that this alteration in neurobiological reward processing may predate significant weight gain or potentially predispose an individual to obesity. Together, these findings suggest that obesity is related to alterations in neural response to reward beyond food, with elevated activation in reward‐related brain circuitry and reduced activation in cortical regions linked to inhibitory control.…”

Section: Introductionmentioning

confidence: 99%

Double jeopardy: Comorbid obesity and cigarette smoking are linked to neurobiological alterations in inhibitory control during smoking cue exposure

et al. 2019

Self Cite

View full text Add to dashboard Cite

Obesity and cigarette smoking are two of the leading preventable causes of death in the United States. Research suggests that overlapping pathophysiology may contribute to obesity and nicotine use disorder (NUD), yet no studies have investigated the effect of obesity on neural response to reward stimuli in NUD. This study used arterial spin-labeled perfusion functional magnetic resonance imaging (fMRI) to examine neural responses during exposure to smoking versus nonsmoking cues in 79 treatment-seeking participants with NUD, 26 with normal weight, 28 with overweight, and 25 with obesity. Given that deficits in behavioral inhibitory control have been associated with both obesity and NUD, participants completed an affectcongruent Go/NoGo task to assess the effect of body mass index (BMI) on this construct in NUD. Analyses revealed that BMI was negatively associated with activation in the right dorsolateral prefrontal cortex (dlPFC) in response to smoking cues, with significantly reduced response in smokers with overweight and smokers with obesity compared with normal-weight smokers. In addition, greater commission errors on the Go/NoGo task were correlated with reduced neural response to smoking cues in the right dlPFC only among those with obesity. Together, these findings provide evidence that obesity in treatment-seeking NUDs is related to neurobiological alterations in inhibitory control over cue-potentiated behaviors, suggesting that smoking cessation may be more difficult in individuals with comorbid NUD and obesity than in those without, requiring treatment strategies tailored to meet their unique needs.

show abstract

2. Chronic Disease Epidemiology

Redwood¹,

Remington²,

Brownson³

2016

CHRONIC DISEASE EPIDEMIOLOGY, PREVENTION, AND CONTROL, 4th Edition

View full text Add to dashboard Cite

The way to her heart? Response to romantic cues is dependent on hunger state and dieting history: An fMRI pilot study

Cited by 3 publications

References 60 publications

The effect of preprocessing pipelines in subject classification and detection of abnormal resting state functional network connectivity using group ICA

The effect of preprocessing pipelines in subject classification and detection of abnormal resting state functional network connectivity using group ICA

Double jeopardy: Comorbid obesity and cigarette smoking are linked to neurobiological alterations in inhibitory control during smoking cue exposure

2. Chronic Disease Epidemiology

Contact Info

Product

Resources

About