The viability of SARS-CoV-2 on solid surfaces

Hosseini, Mirza Hassan; Behzadinasab, Saeed; Benmamoun, Zachary; Ducker, William A.

doi:10.1016/j.cocis.2021.101481

Cited by 49 publications

(54 citation statements)

References 79 publications

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“…Another important area that is receiving increasing attention is the advancement of antiviral coatings to fight the deadly COVID-19 disease [199]. Researchers have been working throughout the current pandemic to develop the next generation of antimicrobial materials to reduce the spread of infection via high touch surfaces as well as PPE surfaces [4], which account for around 20% of total infections among healthcare workers [200].…”

Section: Anti-sars-cov-2 Coatingsmentioning

confidence: 99%

Recent Advances in Metal-Based Antimicrobial Coatings for High-Touch Surfaces

Birkett

Dover

Lukose

et al. 2022

IJMS

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International interest in metal-based antimicrobial coatings to control the spread of bacteria, fungi, and viruses via high contact human touch surfaces are growing at an exponential rate. This interest recently reached an all-time high with the outbreak of the deadly COVID-19 disease, which has already claimed the lives of more than 5 million people worldwide. This global pandemic has highlighted the major role that antimicrobial coatings can play in controlling the spread of deadly viruses such as SARS-CoV-2 and scientists and engineers are now working harder than ever to develop the next generation of antimicrobial materials. This article begins with a review of three discrete microorganism-killing phenomena of contact-killing surfaces, nanoprotrusions, and superhydrophobic surfaces. The antimicrobial properties of metals such as copper (Cu), silver (Ag), and zinc (Zn) are reviewed along with the effects of combining them with titanium dioxide (TiO2) to create a binary or ternary contact-killing surface coatings. The self-cleaning and bacterial resistance of purely structural superhydrophobic surfaces and the potential of physical surface nanoprotrusions to damage microbial cells are then considered. The article then gives a detailed discussion on recent advances in attempting to combine these individual phenomena to create super-antimicrobial metal-based coatings with binary or ternary killing potential against a broad range of microorganisms, including SARS-CoV-2, for high-touch surface applications such as hand rails, door plates, and water fittings on public transport and in healthcare, care home and leisure settings as well as personal protective equipment commonly used in hospitals and in the current COVID-19 pandemic.

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Section: Anti-sars-cov-2 Coatingsmentioning

confidence: 99%

Recent Advances in Metal-Based Antimicrobial Coatings for High-Touch Surfaces

Birkett

Dover

Lukose

et al. 2022

IJMS

View full text Add to dashboard Cite

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“…The virus is known to spread via respiratory droplets, 2 close contact with infected individuals, and viral contamination of frequently touched surfaces. 3 As such, government and health authorities have urged the use of personal protective equipment (PPE), such as masks, avoidance of indoor congregation, and disinfection of surfaces. 4 While mask wearing has been shown to mitigate the spread of Covid-19, there is also much resistance to the wearing of masks and closure of schools and popular venues such as theaters, restaurants, and businesses.…”

Section: Introductionmentioning

confidence: 99%

Rapid and Effective Inactivation of SARS-CoV-2 with a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports

Kaya

Khalil

Fetrow

et al. 2022

ACS Appl. Mater. Interfaces

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This paper presents results of a study of a new cationic oligomer that contains end groups and a chromophore affording inactivation of SARS-CoV-2 by visible light irradiation in solution or as a solid coating on paper wipes and glass fiber filtration substrates. A key finding of this study is that the cationic oligomer with a central thiophene ring and imidazolium charged groups gives outstanding performance in both the killing of E. coli bacterial cells and inactivation of the virus at very short times. Our introduction of cationic N -methyl imidazolium groups enhances the light activation process for both E. coli and SARS-CoV-2 but dampens the killing of the bacteria and eliminates the inactivation of the virus in the dark. For the studies with this oligomer in solution at a concentration of 1 μg/mL and E. coli, we obtain 3 log killing of the bacteria with 10 min of irradiation with LuzChem cool white lights (mimicking indoor illumination). With the oligomer in solution at a concentration of 10 μg/mL, we observe 4 log inactivation (99.99%) in 5 min of irradiation and total inactivation after 10 min. The oligomer is quite active against E. coli on oligomer-coated paper wipes and glass fiber filter supports. The SARS-CoV-2 is also inactivated by oligomer-coated glass fiber filter papers. This study indicates that these oligomer-coated materials may be very useful as wipes and filtration materials.

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“…In the last 2 weeks of the study, the Belo Horizonte City population presented an increasing number of positive COVID-19 individuals, and sanitary measures were more restrictive at this moment due to the gravity of the COVID-19 pandemic. Viable SARS-CoV-2 can be detected on surfaces after hours and not viable viral RNA after days according to the material and in laboratory conditions [ 5 ]. In addition, environmental interference, such as temperature, humidity, and heat makes its transmission ability by objects lower than expected in the public environment [ 7 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

Biosafety in Dental Health Care During the COVID-19 Pandemic: A Longitudinal Study

Miguita

Martins‐Chaves

Geddes

et al. 2022

Front. Oral. Health

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BackgroundThe coronavirus disease 2019 (COVID-19) pandemic had quite an impact on dental health care. Concerns about the risk of SARS-CoV-2 transmission through contaminant fluids and droplet formation during several dental procedures highly impacted dental health care, drastically reducing the number of dental practices worldwide. To monitor SARS-CoV-2 contamination in dental clinics, a longitudinal study was carried out during the return of dental practice at university.MethodsDental health care professionals [(DHCPs); teachers, undergraduate dental students, and dental assistants] and patients were screened for SARS-CoV-2 RNA in a dental school clinic environment from 11th January to 12th March 2021 (9 weeks). Serological testing was performed on DHCPs in two-time points. Additionally, samples with low Ct values were sequenced to identify the circulating SARS-CoV-2 variant and possible transmission clusters.ResultsWe found a low number of dental staff (5.8%), patients (0.9%), and environment sites (0.8%) positive for SARS-CoV-2. Most positive cases had asymptomatic to mild symptoms, and two asymptomatic DHCPs presented prolonged infection. In the first week after previous exposure to COVID-19, 16.2% of DHCPs had IgM or IgG antibodies against SARS-CoV-2, and 1/3 of them had undetected antibodies in the last weeks. The variant zeta (P.2) could be detected. No cross-infection was observed between participants.ConclusionOur study suggests that dental practice can be safely executed when adequate control measures and biosafety protocols are applied. DHCP and patient testing, patient telemonitoring, proper use of personal protection equipment, and sanitization of surfaces are essential to avoid SARS-CoV-2 cross-infection in dental practice.

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The viability of SARS-CoV-2 on solid surfaces

Cited by 49 publications

References 79 publications

Recent Advances in Metal-Based Antimicrobial Coatings for High-Touch Surfaces

Recent Advances in Metal-Based Antimicrobial Coatings for High-Touch Surfaces

Rapid and Effective Inactivation of SARS-CoV-2 with a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports

Biosafety in Dental Health Care During the COVID-19 Pandemic: A Longitudinal Study

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