The Versatility of Collagen in Pharmacology: Targeting Collagen, Targeting with Collagen
Francisco Revert-Ros,
Ignacio Ventura,
Jesús A. Prieto-Ruiz
et al.
Abstract:Collagen, a versatile family of proteins with 28 members and 44 genes, is pivotal in maintaining tissue integrity and function. It plays a crucial role in physiological processes like wound healing, hemostasis, and pathological conditions such as fibrosis and cancer. Collagen is a target in these processes. Direct methods for collagen modulation include enzymatic breakdown and molecular binding approaches. For instance, Clostridium histolyticum collagenase is effective in treating localized fibrosis. Polypepti… Show more
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