The Vellore screening instruments and strategies for the diagnosis of dementia in the community

Stanley, Rena; Kuruvilla, Anju; Kumar, Surendra; Gayathri, K; Mathews, Prasad; Abraham, Vinod Joseph; Rajkumar, Anto P.; Jacob, K. S.

doi:10.1017/s104161020900903x

Cited by 19 publications

(24 citation statements)

References 22 publications

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“…The recently developed Vellore Screening Instrument for Dementia seems promising, but with 10 cognitive and 10 informant items it may be too long for routine use. Furthermore, its only community validation to date was on a sample of only 101 participants, three of whom were diagnosed with dementia (Stanley et al , 2009). …”

Section: Introductionmentioning

confidence: 99%

A brief dementia screener suitable for use by non‐specialists in resource poor settings—the cross‐cultural derivation and validation of the brief Community Screening Instrument for Dementia

Prince

Acosta

Ferri

et al. 2010

Int J Geriat Psychiatry

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100

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ObjectiveBrief screening tools for dementia for use by non-specialists in primary care have yet to be validated in non-western settings where cultural factors and limited education may complicate the task. We aimed to derive a brief version of cognitive and informant scales from the Community Screening Instrument for Dementia (CSI-D) and to carry out initial assessments of their likely validity.MethodsWe applied Mokken analysis to CSI-D cognitive and informant scale data from 15 022 participants in representative population-based surveys in Latin America, India and China, to identify a subset of items from each that conformed optimally to item response theory scaling principles. The validity coefficients of the resulting brief scales (area under ROC curve, optimal cutpoint, sensitivity, specificity and Youden's index) were estimated from data collected in a previous cross-cultural validation of the full CSI-D.ResultsSeven cognitive items (Loevinger H coefficient 0.64) and six informant items (Loevinger H coefficient 0.69) were selected with excellent hierarchical scaling properties. For the brief cognitive scale, AUROC varied between 0.88 and 0.97, for the brief informant scale between 0.92 and 1.00, and for the combined algorithm between 0.94 and 1.00. Optimal cutpoints did not vary between regions. Youden's index for the combined algorithm varied between 0.78 and 1.00 by region.ConclusionA brief version of the full CSI-D appears to share the favourable culture- and education-fair screening properties of the full assessment, despite considerable abbreviation. The feasibility and validity of the brief version still needs to be established in routine primary care. Copyright © 2010 John Wiley & Sons, Ltd.

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Section: Introductionmentioning

confidence: 99%

A brief dementia screener suitable for use by non‐specialists in resource poor settings—the cross‐cultural derivation and validation of the brief Community Screening Instrument for Dementia

Prince

Acosta

Ferri

et al. 2010

Int J Geriat Psychiatry

Self Cite

100

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“…Stanley et al [20] reported the unacceptable false-positive rates of a screening instrument for dementia when used in the community as compared to hospital use. Chan et al [21] studied whether a screening questionnaire for parkinsonism yielded similar results when used in the hospital and community setting in Australia, and found that results do tend to differ between the two.…”

Section: Discussionmentioning

confidence: 99%

Hospital and Community Validation of a Screening Instrument for Detection of Neurodisability in Indian Children Aged 6 Months to 2 Years

Bhave

Bhargava²,

Rizvi³

et al. 2011

Neuroepidemiology

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Objective: To develop and validate a screening instrument for neurological disorders in children aged 6 months to 2 years in the community. Methods: A comprehensive parent-administered instrument was developed to screen for hearing, vision, seizures, motor deficits and development in Indian children aged 6–24 months. This was tested for reliability and validated in the hospital setting by comparing with pre-decided gold standards. It was then used in a community survey in a two-phase design in which all screen positives and a random sample of screen negatives were validated. Result: The screening instrument had overall sensitivity, specificity and positive predictive values of 95.8, 68.1 and 76.1%, respectively, in the hospital setting. In the field setting, these figures changed to 95.4, 51.8 and 20.6%, respectively. The reasons for this are discussed. Conclusion: Community surveys must use a two-phase design to get the true prevalence. A falsely high prevalence will be computed if only a single-phase design or hospital validation is used.

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“…Using the 10/66 dementia research group algorithm, a higher prevalence rate for dementia was found (urban Chennai: 7.5 % and rural Vellore: 10.6 %) (Llibre Rodriguez et al 2008). Vellore screening instrument was developed after employing the 'activities of daily living', which are not influenced by education and culture and can reduce the false-positive rates in community studies (Stanley et al 2009). …”

Section: Dementiamentioning

confidence: 99%

Geriatric Psychiatry in India: Developments and Future Directions

Khandelwal

Pattanayak

2015

Developments in Psychiatry in India

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The Vellore screening instruments and strategies for the diagnosis of dementia in the community

Abstract: The patient screen and the informant version are short culture- and education-fair instruments. They reduce false positive rates, when used in combination in the community.

Cited by 19 publications

References 22 publications

A brief dementia screener suitable for use by non‐specialists in resource poor settings—the cross‐cultural derivation and validation of the brief Community Screening Instrument for Dementia

A brief dementia screener suitable for use by non‐specialists in resource poor settings—the cross‐cultural derivation and validation of the brief Community Screening Instrument for Dementia

Hospital and Community Validation of a Screening Instrument for Detection of Neurodisability in Indian Children Aged 6 Months to 2 Years

Geriatric Psychiatry in India: Developments and Future Directions

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