“…A number of anatomical landmarks have been proposed to achieve correct rotational alignment, such as the posterior condylar axis (PCA), surgical transepicondylar axis, clinical transepicondylar axis (CEA), and anteroposterior trochlear axis (i.e., Whiteside's anteroposterior axis) (3,4). The transepicondylar axis has been demonstrated, in theory, to be a reliable rotational reference line for properly placing the femoral component (5-7), but identifying it intraoperatively is difficult in some cases because of the low-profile geometry of and/or soft tissues covering the epicondyles (8,9). Therefore, surgeons typically estimate the transepicondylar axis from the PCA by using the twist angle determined on preoperative X-rays or computed tomography (CT) scans and set the cutting guide based on these measurements.…”