The value of twice yearly bronchoscopy in the work-up and follow-up of patients with laryngeal cancer

Rachmat, L.; Manni, Johannes J.; Vreeburg, G. C. M.; Vries, Nico de; Snow, Gordon B.; Hordijk, G. J.; Lubsen, H.

doi:10.1016/s0959-8049(05)80295-3

Cited by 21 publications

(12 citation statements)

References 22 publications

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“…Rachmat et al studied 170 patients with laryngeal cancer who were followed up by twice yearly bronchoscopy with sputum cytology. 44 Five second primary tumours and six metastases in the lung were discovered. The patients found the procedure unpleasant, an emotional burden and time-consuming.…”

Section: Endoscopymentioning

confidence: 99%

Current concepts of surveillance and its significance in head and neck cancer

Manikantan

Dwivedi

Sayed

et al. 2011

annals

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Follow-up in head and neck cancer (HNC) is essential to detect and manage locoregional recurrence or metastases, or second primary tumours at the earliest opportunity. A variety of guidelines and investigations have been published in the literature. This has led to oncologists using different guidelines across the globe. The follow-up protocols may have unnecessary investigations that may cause morbidity or discomfort to the patient and may have significant cost implications. In this evidencebased review we have tried to evaluate and address important issues like the frequency of follow-up visits, clinical and imaging strategies adopted, and biochemical methods used for the purpose. This review summarises strategies for follow-up, imaging modalities and key investigations in the literature published between 1980 and 2009. A set of recommendations is also presented for cost-effective, simple yet efficient surveillance in patients with head and neck cancer.

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Section: Endoscopymentioning

confidence: 99%

Current concepts of surveillance and its significance in head and neck cancer

Manikantan

Dwivedi

Sayed

et al. 2011

annals

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“… 6 However, an attempt to screen for second primaries within the lung using bronchoscopy, in patients previously treated for laryngeal cancer, has proven unsuccessful. 7 Second primaries may also present within the abdomen. McGarry et al .…”

mentioning

confidence: 99%

Chest computerized tomography scanning in patients presenting with head and neck cancer

Houghton¹,

McGarry²,

Stewart

et al. 1998

Clin Otolaryngol

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Between 1 to 16% of patients with head and neck squamous cell carcinoma (HNSCC) have synchronous tumours; the majority (> 50%) occurring within the lung. Previous studies have relied upon endoscopy and chest radiographs. The aim of this study was to determine the incidence of synchronous intrapulmonary tumours in this group of patients using computerized tomography (CT) scanning. Over 36 months, 111 consecutive patients were assessed at presentation by contrast enhanced CT scanning from the skull base to the diaphragm. Chest scans showed intrapulmonary lesions in 17 patients and 10 have, with time, been confirmed as neoplastic. These allowed treatment of three primary bronchial carcinomas following radical treatment of the index tumour and cancellation of radical treatment in five patients with metastases. Two patients with possible metastases at presentation underwent radical treatment to the index tumour with subsequent follow-up confirming metastatic chest disease. All 10 patients eventually died of either locoregional or metastatic disease. This is one of the first prospective reports of chest scanning in patients with head and neck cancer. An additional chest scan in this group, many of whom undergo a staging scan of the neck, requires an extra 10 min with no further contrast and in this study yielded a synchronous tumour rate of 9%.

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“…This increased sensitivity of CT scanning may be of benefit in the long-term follow-up of these patients, although it is worth noting that previous studies have shown no benefit to be gained from using chest x-ray of bronchoscopy in the follow-up of head and neck cancer patients. 14,15 At present, we advocate 1-monthly follow-up for the first year, 2-monthly for the second year, 3-monthly for the third year, and 6-monthly for the following 2 years. The aim of this follow-up is the detection of treatable recurrent disease and the identification of second primary tumors.…”

Section: Discussionmentioning

confidence: 99%