The value of the use of plasma B-type natriuretic peptide among acute ischemic stroke patients in a Chinese emergency department

A new algorithm of suspected stroke patient management with brain natriuretic peptide/N-terminal pro-brain natriuretic peptide point of care testing platform in the emergency department

“…We have already known that elevated BNP and NT-proBNP level is an independent biomarker for cardioembolic stroke and is associated with unfavorable outcome. [234] In the ED, emergency physician can perform BNP/NT-proBNP test and get the result within 15 min using point of care testing platform. To keep effective and rapid assessment, we set up a new algorithm of suspected stroke patient management in the ED.…”

Experiences and the use of BNP POCT platform on suspected stroke patients by a Chinese emergency department

“…[6] Based on the related guidelines, we set up a clinical study about the use of BNP among acute stroke patients in our ED. [7] We suggest to add plasma BNP test at bedside to the third step of the AHA and ASA stroke guidelines in the ED. The suspected stroke patients could be obtained intravenous (IV) access and performed laboratory assessments within 10 min of arrival at the ED.…”

“…The common target is to recognize the patients with cardioembolic stroke as soon as possible, due to high risks and poor long-term outcome, including death. [234567] Based on a lot of published studies, the BNP testing at bedside on admission, could be suggested to add into early stroke management guidelines as a strategy for improving stroke subtype classification, predict the development of atrial fibrillation after admission, and risk stratification. Thus, rapidly guiding other diagnostic tests and accelerating the start of optimal secondary prevention (e.g., control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke), further diagnostic examination, intensive rehabilitative intervention, and ultimately better patient outcomes.…”

“…It is sensitive, specific, easy, rapidly processed, inexpensive, and widely available; suggesting that the plasma BNP could be a potential and good stroke biomarker for emergency physicians’ use. [2345678]…”

Comparison of Serum Soluble Corin Levels among Stroke Subtypes

“…And B-type natriuretic peptide had diagnostic value to identify cadioembolic subtype from other ischemic stroke subtypes [19,20]. As we know, corin can convert natriuretic peptides from inactive precursors to mature active forms [6,7].…”