The value of the platelet/high-density lipoprotein cholesterol ratio in predicting depression and its cardiovascular disease mortality: a population-based observational study
Huifeng Zhang,
Ying Xu,
Yaying Xu
Abstract:BackgroundCardiovascular disease (CVD) and depression have a bidirectional association, with inflammation and metabolic factors being common important triggers for both conditions. However, as a novel inflammatory and metabolic marker, platelet-to-HDL-C ratio (PHR) has not been established in relation to depression and cardiovascular disease.Materials and methodsParticipants aged 20 years and older were included in the 2005–2018 NHANES database. PHR was calculated as the ratio of platelet count (1000 cells/μL)… Show more
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