THE value of gallium<sup>07</sup> scanning in the evaluation of head and neck malignancy

Nj, Smith; Teates, Charles D.; Am, El-Mahdi; Gs, Fitz-Hugh; Wc, Constable

doi:10.1288/00005537-197505000-00002

Cited by 12 publications

(1 citation statement)

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“…Further investigation is underway to validate the role of 67 Ga scan in the therapeutic control of PCM. 67 Ga imaging has been reported to be of limited value in the evaluation of pathological neck processes owing to the increased physiological uptake in this region [11]. Nevertheless, our results showed that 67 Ga scintigraphy was useful in detecting laryngeal PCM involvement when acute inflammatory lesions were visible on laryngoscopy.…”

Section: Discussionmentioning

confidence: 56%

The role of gallium-67 scan in defining the extent of disease in an endemic deep mycosis, paracoccidioidomycosis: a predominantly multifocal disease

Yamaga

Benard

Hironaka

et al. 2003

Eur J Nucl Med Mol Imaging

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The tools currently used to evaluate the extent of paracoccidioidomycosis (PCM) may be of limited value in detecting subclinical lesions. The aim of this study was to verify the role of gallium-67 whole-body scan in evaluating the extent of disease of 65 patients with active PCM. The (67)Ga scan findings were compared with the results of clinical evaluation, chest radiography and/or high-resolution computed tomography (CT), abdominal ultrasound (US) or CT, laryngoscopy, CT or magnetic resonance imaging (MRI) of the head, and technetium-99m methylene diphosphonate bone scan, obtained before treatment. Clinically unsuspected lesions were detected by imaging procedures in 21 patients (32%), mainly in the lungs (n=11), adrenals (n=6), and superficial (n=3) and deep lymph nodes (n=14). (67)Ga scan detected 100% of the cases with subclinical involvement in the lungs. Scintigraphy was superior to chest radiography in demonstrating lung disease (94% vs 81%). The lymphatic lesions were demonstrated by (67)Ga scan in all the clinically suspected cases and in nearly all unsuspected cases, and also revealed more extensive involvement than was clinically suspected in many of them. There was good agreement between (67)Ga scan and the other imaging procedures for the initial detection of thoracic and abdominal lymph nodes and bone involvement. (67)Ga imaging detected most cases of laryngopharyngeal disease with active inflammatory lesions found at indirect laryngoscopy. On the other hand, (67)Ga scan failed to demonstrate most of the adrenal and CNS lesions detected by abdominal US/CT and head CT/MRI. In conclusion, (67)Ga imaging is a useful tool for evaluating the location and extent of suspected and unsuspected lesions in PCM. It could serve as a screening method before the use of other diagnostic procedures, particularly in the detection of lung, superficial and deep lymph node and bone involvement.

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Section: Discussionmentioning

confidence: 56%

The role of gallium-67 scan in defining the extent of disease in an endemic deep mycosis, paracoccidioidomycosis: a predominantly multifocal disease

Yamaga

Benard

Hironaka

et al. 2003

Eur J Nucl Med Mol Imaging

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The role of nuclear scanning in head and neck surgery

Pretorius

Taylor

1982

Head Neck

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A number of procedures in nuclear medicine are available to assist the surgeon in evaluating pathologic conditions of the head and neck. Gallium-67 citrate scanning is occasionally useful in determining the extent of head and neck tumors but rarely can it detect an occult tumor and it cannot distinguish between an infection and a tumor. Technetium-99m pertechnetate can be used to evaluate diseases of the salivary glands including 123 and technetium-99m pertechnetate are commonly used to obtain images of the thyroid, but some malignant thyroid nodules will accumulate technetium-99m pertechnetate and the suspicious character of the nodule may be only appreciated by iodine scanning. The use of iodine 131 is generally limited to the detection of a substernal thyroid, therapeutic thyroid ablation, and the treatment of hyperthyroidism and thyroid cancer. Bone scanning has been used experimentally to evaluate the healing of mandibular bone grafts and to detect local extension of primary head and neck tumors to skull and facial bones.

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