The value of EUS in predicting the response of gastric mucosa–associated lymphoid tissue lymphoma to Helicobacter pylori eradication

Clinical Trial Report: Eradication of Helicobacter pylori and MALT Lymphoma: Where Do We Stand?

“…Endoscopic ultrasound can determine both of these quite easily. The importance of EUS has been well described in many other previous studies and is considered the standard of care in management of MALT lymphoma patients [2,3]. The third prognostic factor uses genetic analysis of the tumor.…”

Gastric oncology: an update

“…Low-grade MALT lymphoma (stage El1) can be cured with antibiotic therapy aimed at the eradication of H. pylori [61,62]. In appropriately selected patients, this approach is associated with complete remission in 50-100% of patients (Table 2) [56].…”

The role of Helicobacter pylori in the pathogenesis of gastric malignancies

“…Because some of these latter patients probably have concurrent high-grade MALT lymphoma (which is relatively refractory to H. pylori eradication), it is recommended that they undergo multiple gastric biopsies and endoscopic ultrasound prior to antibiotic administration. This will establish the tumor grade and thoroughly evaluate the depth of the tumor and associated lymphadenopathy [70,71]. Once the clinical stage and histology are determined, treatment should be individualized and should vary from H. pylori eradication therapy alone (in localized, low-grade tumors) to chemotherapy, radiation therapy, and possibly surgery.…”