The Value of Carcinoembryonic Antigen Staining to Determine the Primary Malignancy in Metastatic Carcinoma to the Gingiva

Nishide, Naoto; Kanamura, Narisato

doi:10.1097/01.coc.0000164005.25685.13

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…Nishide and Kanamura reported on a soft tissue oral metastasis in a patient with a history of metachronous primary cancers, namely endometrial and gastric adenocarcinomas. Following discovery of an oral lesion, the gingival mass was subsequently diagnosed as a metastatic gastric adenocarcinoma based on both histopathologic similarity and CEA immunoreactivity (Nishide and Kanamura, 2006).…”

Section: Discussionmentioning

confidence: 99%

Gastric adenocarcinoma metastases to the alveolar mucosa of the mandible: A case report and review of the literature

Sauerborn

Vidaković

Baranović

et al. 2011

Journal of Cranio-Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Gastric adenocarcinoma metastases to the alveolar mucosa of the mandible: A case report and review of the literature

Sauerborn

Vidaković

Baranović

et al. 2011

Journal of Cranio-Maxillofacial Surgery

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“…1,3,6,7 When the oral metastasis is identified first, the prognosis is poor due to widespread metastasis of the tumor cells. 1,[3][4][5][6] There is no effective treatment for patients with oral cavity metastasis so far, and local surgical resection has been empirically chosen to avoid artification disorder or dysmasesis. Chemoradiation therapy is also performed for the management of general metastasis following the standard regimen targeted to the primary site.…”

mentioning

confidence: 99%

Gingival Metastasis from Rectal Cancer

Kusumoto

Nakabayashi²,

Otsuka³

et al. 2008

Journal of Gastrointestinal Surgery

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Oral metastasis of pulmonary adenocarcinoma: diagnosis and treatment

Picot

Jouan

et al. 2019

J Oral Med Oral Surg

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Introduction: Oral metastases are rare and represent 1% oro-facial neoplasms. The lung is the most common primary site for oral metastatic tumors. The diagnosis is based on histological analysis. Oral metastases have been associated with poor prognosis and is no longer a proven treatment. It was found in a 58-year old man diagnosed with lung cancer with a voluminous mandibular tumefaction following dental avulsion. The panoramic X-ray showed an area of osteolysis compared to the extraction site. The histological and immunohistochemistry of the lesion showed a positivity of the marker CK7 and a negativity of TTF1, in favor of a lung origin. The biomolecular analysis revealed a mutation on the BRAF gene confirming the metastasis primitive origin. Treatment by surgical resection was performed palliatively. Comments: The diagnosis of an oral metastasis remains difficult and is based on the histological analysis and finding immune markers. Molecular biology is sometimes required for theranostics. Treatment options include surgical resection, radiotherapy, and/or chemotherapy. They are sometimes limited to preserve the quality of life. The prognosis of patients with oral metastases is very poor. Conclusion: Oral metastases are rare, and the diagnosis remains difficult.

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The Value of Carcinoembryonic Antigen Staining to Determine the Primary Malignancy in Metastatic Carcinoma to the Gingiva

Cited by 4 publications

References 4 publications

Gastric adenocarcinoma metastases to the alveolar mucosa of the mandible: A case report and review of the literature

Gastric adenocarcinoma metastases to the alveolar mucosa of the mandible: A case report and review of the literature

Gingival Metastasis from Rectal Cancer

Oral metastasis of pulmonary adenocarcinoma: diagnosis and treatment

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