The value of auto-adjustable CPAP devices in pressure titration and treatment of patients with obstructive sleep apnea syndrome

Hertegonne, Katrien; Bauters, F

doi:10.1016/j.smrv.2009.07.001

Cited by 26 publications

(16 citation statements)

References 69 publications

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“…Moreover, in our clinical experience, the model we tested is still used by many patients. Furthermore, it is often difficult to compare device behaviour due to the proprietary nature of the technology [31]. However, it is clear that technology differs between autoCPAP devices and our findings cannot be generalised to other devices as their detection and response capabilities may be better or worse.…”

Section: Sleep-related Disordersmentioning

confidence: 84%

Residual sleep-disordered breathing during autotitrating continuous positive airway pressure therapy

Denotti¹,

Wong²,

Dungan³

et al. 2011

Eur Respir J

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Obstructive sleep apnoea (OSA) is often treated with autotitrating continuous positive airway pressure (autoCPAP) devices. Clinical and bench tests of these devices have suggested performance limitations. These studies do not indicate whether this is a failure to detect or a failure to respond to airway obstruction.In this randomised, crossover trial, 34 patients with moderate-to-severe OSA underwent polysomnography on two laboratory visits. The autoCPAP device was randomly set to a fixed subtherapeutic pressure (detection assessment) or autotitrating mode (response assessment). Airflow was measured both from the autoCPAP (autoCPAP flow) and directly from the nasal mask, and recorded on polysomnography. Apnoea/hypopnoea indices (AHIs) measured at the two sites and from the autoCPAP download report were compared.Regarding detection, the AHI measured from the nasal mask showed good agreement with the autoCPAP flow AHI, but agreement was lower with the autoCPAP report AHI. In autotitrating mode, there was significant misclassification of those with and without OSA (AHI o10 events?h -1

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Section: Sleep-related Disordersmentioning

confidence: 84%

Residual sleep-disordered breathing during autotitrating continuous positive airway pressure therapy

Denotti¹,

Wong²,

Dungan³

et al. 2011

Eur Respir J

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show abstract

“…CPAP is the first-line therapy, as a means of maintaining upper airway patency [6], and it is well known that this intervention reduces morbidity and mortality [7]. In severe cases of OSAS, the weight loss strategy is essential and must accompany CPAP treatment [8]. A growing body of evidence in OSAS supports the beneficial role of weight reduction, induced by diet alone [9][10][11][12] or in combination with exercise [13], leading to a reduction in apnoeas and hypopnoeas.…”

Section: #"mentioning

confidence: 99%

Effect of Mediterranean dietversusprudent diet combined with physical activity on OSAS: a randomised trial

Papandreou¹,

Schiza²,

Bouloukaki³

et al. 2011

Eur Respir J

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We aimed to evaluate the effect of the Mediterranean diet (MD) compared with a prudent diet (PD) combined with physical activity on obese obstructive sleep apnoea syndrome (OSAS) patients who were treated with continuous positive airway pressure. 900 patients were evaluated and 40 obese patients (body mass index o30.0 kg?m -2 ) who met the inclusion criteria, with moderate-to-severe OSAS (apnoea-hypopnoea index (AHI) .15 events?h -1 and Epworth Sleepiness Scale score .10) based on overnight attended polysomnography, were included in the study. After randomisation, 20 patients followed the MD and 20 a PD for a 6-month period. All patients were counselled to increase their physical activity.Concerning sleep parameters, only AHI during rapid eye movement (REM) sleep was reduced to a statistically significant degree, by mean¡SD 18.4¡17.6 events?h Our results showed that the MD combined with physical activity for a 6-month period was effective in reducing the AHI during REM sleep without any statistically significant effect in the other sleep parameters, compared with a PD in obese adults with moderate-to-severe OSAS.

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“…A fundamental role is played by the apnoeainduced hypoxia. Continuous Positive Airway Pressure (CPAP) is the main therapeutic device used to correct the hypoxia related to sleep disorders causing breathing difficulties [12].…”

Section: Introductionmentioning

confidence: 99%

Reversibility of the endothelial dysfunction after CPAP therapy in OSAS patients

Ciccone

Favale

Scicchitano

et al. 2012

International Journal of Cardiology

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The value of auto-adjustable CPAP devices in pressure titration and treatment of patients with obstructive sleep apnea syndrome

Cited by 26 publications

References 69 publications

Residual sleep-disordered breathing during autotitrating continuous positive airway pressure therapy

Residual sleep-disordered breathing during autotitrating continuous positive airway pressure therapy

Effect of Mediterranean dietversusprudent diet combined with physical activity on OSAS: a randomised trial

Reversibility of the endothelial dysfunction after CPAP therapy in OSAS patients

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