The Value of Aneurysm Volume and Myocardial Strain Rate for Evaluating Cardiac Function of Ischemia‐Related Left Ventricular Aneurysm in a Rabbit Model Using Real Time Three‐Dimensional Echocardiographic Imaging Combined with Speckle Tracking Imaging

Zhang, Hong; Mu, Yuming; Guan, Lina; Li, Yanhong

doi:10.1111/echo.12144

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…Children were scanned in a left lateral decubitus position in a common situation except for dextrocardia in the right decubitus position. 3DE was performed using an iE33 ultrasound machine (Philips, Andover, MA, USA) with a matrix‐array transducer (X5‐1, X7‐2). Before acquisition, echocardiographic images were optimized for endocardial border visualization.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of Left Ventricular Volumes and Function by Real Time Three‐Dimensional Echocardiography in Children with Functional Single Left Ventricle: A Comparison between QLAB and TomTec

et al. 2015

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Section: Methodsmentioning

confidence: 99%

Evaluation of Left Ventricular Volumes and Function by Real Time Three‐Dimensional Echocardiography in Children with Functional Single Left Ventricle: A Comparison between QLAB and TomTec

et al. 2015

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“…These lesions were present in our case. In humans, CVAs may cause clinical signs even during childhood and AVA at a later stage in life, as the primary cause in most cases is atherosclerosis (MARIJON et al, 2006;ZHAI et al, 2013).…”

Section: Montagnini Et Almentioning

confidence: 99%

Biventricular aneurysm in a dog

Montagnini,

Ferronato,

Smaniotto

et al. 2024

Cienc. Rural

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An aneurysm is defined as a localized dilation of a blood vessel or heart. It may have either a congenital or an acquired origin and occurs in both humans and animals. Cardiac aneurysms are rare, and are characterized by sacculations of the cardiac wall. The present case report describes the macroscopic and microscopic findings of an aneurysm affecting both ventricles of the heart in a dog. A 7-year-old mixed-breed female dog with osteosarcoma on the left pelvic limb was euthanized and submitted to the veterinary pathology laboratory for necropsy. Macroscopically, besides the lesions in the link, the pericardial sac was adhered to the pericardial surface of the heart and there were two sacculations in both ventricles which communicated widely with the respective ventricle. Microscopically, fibrous tissue adhered to the pericardium, atrophy and necrosis of the cardiomyocytes with replacement by adipocytes were observed in addition to hyperplasia of the tunica media of arterioles and thrombosis. A diagnosis of acquired biventricular cardiac aneurysm was made based on the necropsy findings and microscopic lesions in the heart. We emphasize the importance of performing a necropsy and examining tissues histologically for the diagnosis of this rare condition. Ventricular aneurysms should be included in the differential diagnosis of cardiovascular disease in dogs.

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“…2.6.1 Speckle tracking echocardiography Speckle tracking echocardiography (STE) technique is an innovation technique. It is more sensitive for detection of early myocardial infarction in patients than standard echocardiography (Zhai et al, 2013). STE was derived from TDI to perform myocardial velocities and deformation due to limitation of TDI, which is angle dependent.…”

Section: Standard Echocardiographymentioning

confidence: 99%

Effects of amiodarone and dronedarone on heart rate variability, cardiac contractility, and thyroid hormone levels in rabbits

Boonhoh

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Amiodarone (AM) and dronedarone (DR) are class III antiarrhythmic agents that have similar chemical structures, except AM contains iodine molecules. Due to the limited data available in rabbits, the effects of both drugs on heart rate variability (HRV), contractility and thyroid hormone levels were studied. Sixteen male New Zealand white rabbits were used and divided into 2 groups received AM or DR. The rabbits were gavaged either AM or DR at dosages of 50 (AM50, DR50) and 100 mg/kg/day (AM100, DR100) continuously for a period of 7 days each. On the last day of each period, electrocardiograms were recorded from the conscious rabbits, while standard echocardiograms (Echo), speckle tracking echocardiograms (STE) and blood samples were collected from the anesthetized rabbits afterward. The HRV results showed that AM100 and DR100 decreased heart rate, total power, low frequency component, and low to high frequency ratio significantly compared to the baselines. All echocardiographic parameters of both agents in every period were no significant difference from their baselines, except global circumferential plane strain rate at basal segmental level of AM50 that was decreased. Thyroxine levels were significantly increased in AM treatments but decreased in DR treatments of treatment period 1 and 2 compared to their baseline. In conclusion, both AM and DR reduce HRV which may be due to sympathetic suppression. STE may provide more information but not give higher sensitivity than Echo in our study, despite the fact that AM may have more negative inotropic effect than DR in this model. Nevertheless, both drugs produced thyroid dysfunction in the different way, thyrotoxicosis in AM but hypothyroidism in DR.

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The Value of Aneurysm Volume and Myocardial Strain Rate for Evaluating Cardiac Function of Ischemia‐Related Left Ventricular Aneurysm in a Rabbit Model Using Real Time Three‐Dimensional Echocardiographic Imaging Combined with Speckle Tracking Imaging

Abstract: LVA volume/LVEDV provided a sensitive indicator reflecting cardiac function with LVA. Measurement of various parameters using RT-3DE might be a useful means to evaluate cardiac function after LVA formation.

Cited by 4 publications

References 24 publications

Evaluation of Left Ventricular Volumes and Function by Real Time Three‐Dimensional Echocardiography in Children with Functional Single Left Ventricle: A Comparison between QLAB and TomTec

Evaluation of Left Ventricular Volumes and Function by Real Time Three‐Dimensional Echocardiography in Children with Functional Single Left Ventricle: A Comparison between QLAB and TomTec

Biventricular aneurysm in a dog

Effects of amiodarone and dronedarone on heart rate variability, cardiac contractility, and thyroid hormone levels in rabbits

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