The validity of the ‘General Practice Physical Activity Questionnaire’ against accelerometery in patients with chronic kidney disease

Wilkinson, Thomas J; Palmer, Jared; Gore, Eleanor; Smith, Alice C.

doi:10.1080/09593985.2020.1855684

Cited by 8 publications

(9 citation statements)

References 31 publications

(42 reference statements)

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“…A number of questionnaires were completed at each study visit. The General Practice Physical Activity Questionnaire which has been validated in people living with kidney disease ( 48 ) classified PA into four categories: inactive, moderately inactive, moderately active and active ( 49 ). The Nutrition Self-Efficacy Scale and the Physical Exercise Self-Efficacy Scales ( 50 ) assessed self-efficacy.…”

Section: Methodsmentioning

confidence: 99%

The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients—The ExeRTiOn2 Trial

et al. 2022

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Half of kidney transplant recipients (KTRs) gain more than 5% of their body weight in the first year following transplantation. KTRs have requested support with physical activity (PA) and weight gain prevention, but there is no routine care offered. There are few high-quality studies investigating the clinical value of diet, PA or combined interventions to prevent weight gain. The development and evaluation of theoretically informed complex-interventions to mitigate weight gain are warranted. The aims of this mixed-methods randomized controlled trial (RCT) were to explore the feasibility, acceptability and user-experience of a digital healthcare intervention (DHI) designed to prevent post-transplant weight gain, in preparation for a large multi-center trial. New KTRs (<3 months) with access to an internet compatible device were recruited from a London transplant center. The usual care (UC) group received standard dietary and PA advice. The intervention group (IG) received access to a 12-week DHI designed to prevent post-transplant weight gain. Primary feasibility outcomes included screening, recruitment, retention, adherence, safety and hospitalizations and engagement and experience with the DHI. Secondary outcomes (anthropometrics, bioimpedance, arterial stiffness, 6-minute walk distance and questionnaires) were measured at baseline, 3- and 12-months. 38 KTRs were screened, of which 32 (84.2%) were eligible, and of those 20 (62.5%) consented, with 17 participants (85%) completing baseline assessment (Median 49 years, 58.8% male, Median 62 days post-transplant). Participants were randomized using a computer-generated list (n = 9 IG, n = 8 UC). Retention at 12-months was 13 (76.4%) (n = 6 IG, n = 7 UC). All a priori progression criteria were achieved. There were no associated adverse events. Reflexive thematic analysis revealed four themes regarding trial participation and experience whilst using the DHI. Halting recruitment due to COVID-19 resulted in the recruitment of 40% of the target sample size. Mixed-methods data provided important insights for future trial design. A definitive RCT is warranted and welcomed by KTRs.Clinical Trial Registrationwww.clinicalTrials.gov, identifier: NCT03996551.

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Section: Methodsmentioning

confidence: 99%

The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients—The ExeRTiOn2 Trial

et al. 2022

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“…The GPPAQ is a validated screening tool utilised in primary care settings, as well as being validated within the CKD population in comparison to accelerometery. 22 23 The GPPAQ can accurately identify those not sufficiently active, identifying individuals most at need of a PA intervention. 23 The SEE scale, provided information on each participant's readiness to commence exercise.…”

Section: Methodsmentioning

confidence: 99%

“…22 23 The GPPAQ can accurately identify those not sufficiently active, identifying individuals most at need of a PA intervention. 23 The SEE scale, provided information on each participant's readiness to commence exercise. Self-efficacy scales for eating and exercise behaviours show evidence of being reliable and valid in the literature.…”

Section: Methodsmentioning

confidence: 99%

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Cultural influences on physical activity and exercise beliefs in patients with chronic kidney disease: ‘The Culture-CKD Study’—a qualitative study

et al. 2022

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ObjectivesThis study used a mixed-method approach to explore cultural and ethnic influences on the perception of, and decision to engage with or not to engage with, physical activity and exercise therapy in patients with chronic kidney disease (CKD).DesignQualitative research was conducted through the use of semistructured interviews and focus groups. Self-reported physical activity levels were measured using the General Practice Physical Activity Questionnaire (GPPAQ), and self-efficacy for exercise with Bandura’s Self-Efficacy for Exercise Scale.SettingThis study was conducted in a non-clinical setting of a single National Health Service Hospital Trust between April 2018 and July 2019.ParticipantsParticipants >18 years of age with a diagnosis of CKD, from black African, black Caribbean, South Asian or white ethnicity were eligible for the study. 84 patients with a diagnosis of CKD (stages 2–5), aged 25–79 (mean age 57) were recruited. Semistructured interviews (n=20) and six single-sex, ethnic-specific focus group discussions were undertaken (n=36).OutcomesPrimary outcome was to explore the perceptions, attitudes and values about exercise and physical activity in different ethnic groups through qualitative interviews, analysed using an inductive thematic analysis approach. Questionnaires were analysed using Pearson correlation to determine if there was a significant relationship between the self-efficacy and GPPAQ levels.ResultsQualitative analysis provided four primary themes: I am who I am, Change of identity, Influences to physical activity and exercise and Support and education. Quantitative analysis using Pearson correlation revealed a significant correlation between GPPAQ levels of activity and self-efficacy to regulate exercise behaviour (r=−0.40, p=0.001).ConclusionUnderstanding the cultural, attitudes and beliefs of individuals with CKD from a variety of ethnic backgrounds is complex. Understanding of patients’ experiences, thoughts and beliefs may be of relevance to clinicians when designing CKD exercise services.Trial registration numberNCT03709212; Pre-results.

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“…General Practice Physical Activity Questionnaire (GPPAQ): The GPPAQ was developed by the World Health Organization and Department of Health detailing a 4-level Physical Activity Index (PAI) reflecting an individual’s current physical activity. The GPPAQ is a validated measure of physical activity behaviour in CKD 31 .…”

Section: Methods and Analysismentioning

confidence: 99%

‘Self-Management Intervention through Lifestyle Education for Kidney health’ (the SMILE-K study): protocol for a single-blind longitudinal randomised control trial with nested pilot study

Lightfoot

Wilkinson

Yates

et al. 2022

Preprint

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IntroductionMany people living with chronic kidney disease (CKD) are expected to self-manage their condition. Patient activation is the term given to describe the knowledge, skills, and confidence a person has in managing their own health and is closely related to the engagement in preventive health behaviors. Self-management interventions have the potential to improve remote disease management and health outcomes. We are testing an evidence- and theory-based digital self-management structured 10-week programme developed for CKD patients called ‘My Kidneys & Me’. The primary aim of the study (SMILE-K) is to assess the effect on patient activation levels.Methods and analysisA single-blind randomised control trial (RCT) with a nested pilot study will assess the feasibility of the intervention and study design before continuation to a full RCT. Individuals aged 18 years or older, with established CKD stage 3-4 (eGFR of 15-59 ml/min/1.73m2) will be recruited through both primary and secondary care pathways. Participants will be randomised into two groups: intervention group and control group. The primary outcome is the Patient Activation Measure (PAM-13). The full RCT will assess the effect of the programme on online self-reported outcomes which will be assessed at baseline, after 10-weeks, and then after 20-weeks in both groups. A total sample size of n=432 participants are required based on a 2:1 randomisation. A sub-study will measure physiological changes (e.g., muscle mass, physical function) and patient experience (qualitative semi-structured interviews).Ethics and disseminationThis study was fully approved by the Research Ethics Committee-Leicester South on the 19/11/2020 (reference: 17/EM/0357). All participants are required to provide informed consent obtained online. The results are expected to be published in scientific journals and presented at clinical research conferences. This is protocol version 1.0 dated 27/01/2021.Trial registration numberThe study was prospectively registered as ISRCTN18314195 in December 2020.

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The validity of the ‘General Practice Physical Activity Questionnaire’ against accelerometery in patients with chronic kidney disease

Cited by 8 publications

References 31 publications

The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients—The ExeRTiOn2 Trial

The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients—The ExeRTiOn2 Trial

Cultural influences on physical activity and exercise beliefs in patients with chronic kidney disease: ‘The Culture-CKD Study’—a qualitative study

‘Self-Management Intervention through Lifestyle Education for Kidney health’ (the SMILE-K study): protocol for a single-blind longitudinal randomised control trial with nested pilot study

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