The Validity of Radiological Methods in Assessment of Inflammatory Activity and Fibrous Transformation of the Pancreas at Chronic Pancreatitis

Shevchenkо, B.F.; Babiy, A.M.; Gravirovskaya, N.G.; Петішко, О.П.

doi:10.18484/2305-0047.2016.3.240

Cited by 3 publications

(3 citation statements)

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“…Numerous investigations on the Surgery treatment of chronic pancreatitis are devoted to the choice of the most effective method of Surgery treatment, in particular, to various modifications of previously developed operations (Hamanou et al, 2002). As a rule, such long-term indicators of efficiency as control of a pain syndrome and exo-, the endocrine function of the pancreas are compared between groups of patients stratified first of all by type of Surgery intervention (Shevchenko et al, 2016). However, in a meta-analysis and systematic review, Zhao et al (2017), have concluded that although duodenal resections of the pancreatic head have advantages over pancreatoduodenal resection about the duration of the surgery, needs for blood transfusions, duration of hospitalization, weight gaining, and slightly better exocrine function in the long-term period, however, all operations were equally effective in terms of pain control, postoperative complications, endocrine, and exocrine insufficiency.…”

Section: Methodsmentioning

confidence: 99%

Optimal management of early surgery of chronic pancreatitis

Mikheiev

Yareshko

Vasyl

et al. 2021

ijhs

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The aim of the present research is to investigate whether there are advantages of early surgical treatment or not, especially for pain relief. Retrospective analysis of data of 147 patients from 2001 to 2020 was conducted, which underwent surgical treatment of chronic pancreatitis. Patients who had been suffering from chronic pancreatitis symptoms for 3 years or more were included in the control group (“late surgical treatment”), and patients who had been noting symptoms of chronic pancreatitis less than 3 years were included in the study group (“early surgical treatment”). All patients completed the EORTC QLQ-30, SF-36 questionnaires, as well as the questionnaire developed by the research authors, via telephone or mail or during the visit. According to all scales of the SF 36 questionnaire, except for “Physical functioning”, the group of “Early surgical treatment” prevails over the group of “Late surgical treatment”. The “Early surgical treatment” group had the best average scores on all functional scales of the EORTC QLQ-30 questionnaire compared to the “Late surgical treatment” group, except for the Cognitive Functioning scale. From the symptomatic scales, the “Early surgical treatment” group had the best averages of Pain and Diarrhoea.

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Section: Methodsmentioning

confidence: 99%

Optimal management of early surgery of chronic pancreatitis

Mikheiev

Yareshko

Vasyl

et al. 2021

ijhs

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“…Основна маса досліджень з приводу хірургічного лікування хронічного панкреатиту (ХП) присвячена вибору найбільш ефективного методу оперативного лікування, особливо різним модифікаціям раніше розроблених операцій. Зазвичай порівнюються такі віддалені показники ефективності, як контроль больового синдрому та екзо-, ендокринна функція підшлункової залози (ПЗ) між групами хворих, стратифікованими в першу чергу за видом операції [1]. Однак у метааналізі та систематичному огляді Xin Zhao та співавт.…”

Section: вступunclassified

Optimal time for surgical treatment of chronic pancreatitis or optimal surgery?

Yareshko

Mikheiev

Shpylenko

et al. 2022

GASTRO

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Background. The majority of studies on the surgical treatment of chronic pancreatitis (CP) compare treatment outcomes by the type of the procedure. However, some studies, especially systematic reviews and meta-analyses, indicate the equality of different surgeries by their long-term results. During last 5–9 years, several studies showed advantages of early surgery in chronic pancreatitis, within three years after symptoms onset. Objective: to analyze the short- and long-term results of surgical treatment for chronic pancreatitis regarding timing and, accordingly, the neglect of the disease. Materials and methods. Retrospective analysis of data of 147 patients from 2001 to 2020, the main intervention was surgery aimed at the main manifestations of CP, such as pancreatic ductal and/or parenchymal hypertension. Patients who suffered from CP symptoms 3 years or more were included in the control group (late surgery), and those who noted symptoms of CP for less than 3 years were included in the study group (early surgery). All patients completed the EORTC QLQ-30, SF-36 questionnaires, as well as the questionnaire developed by the study authors, via telephone or mail, or during the visit. Results. According to all scales of the SF-36 questionnaire, except for Physical functioning, the group of early surgery prevails over the group of late surgery. The early surgery group had the best average scores on all functional scales of the EORTC QLQ-30 questionnaire compared to the late surgery group, except for the Cognitive functioning. Of the symptomatic scales, the early surgery group had the best averages on Pain and Diarrhea. The average Health/Quality of life scale was significantly better in the early surgery group. Conclusions. The quality of life, pain control, pancreatic function in patients operated within 3 years from the onset of CP symptoms were better compared to those with longer disease duration, with the same short-term results. The duration of the disease is a major factor for the success of surgical treatment of chronic pancreatitis in terms of long-term results. The early surgery is effective approach to obtain better long-term outcomes in chronic pancreatitis.

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“…Выполнение дренирующих оперативных вмешательств на ПЖ и ее главном протоке приводит к ликвидации гипертензии в вирсунговом протоке и устранению болевого синдрома, но сохраняющиеся и усиливающиеся фиброзновоспалительные изменения в области головки ПЖ, а также наличие кальцификатов в паренхиме поджелудочной железы являются причиной развития осложнений, которые требуют выполнения более сложных резекционных вмешательств [3,4].…”

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Pancreatoduodenal resection in the treatment of complicated forms chronic pancreatitis

Veligotsky

Arutyunov

Klymenko

et al. 2021

Modern Medical Technology

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Purposeof thestudy. Development ofindications for performing pancreatoduodenal resection in complicated forms of chronic pancreatitis. Materials and methods. In chronic pancreatitis, resection and drainage surgical interentions were performed in 142 patients. Pancreatoduodenal resection was performed in 13 patients with complicated forms of chronic pancreatitis. To assess the degree of pancreatic fibrosis, ultrasound elastography was used (in mode Shear Wave Elastography). The indications for pancreatoduodenal resection were the presence of a pronounced fibroinflammatory process in the head of the pancreas, the impossibility of excluding the development of an oncological process, developed complications (biliary hypertension, portal hypertension, duodenal stasis, Results. Among 13 patients with complicated forms of chronic pancreatitis, who underwent pancreatoduodenal resection, 12 (92,3%) patients had severe fibrosis, 1 (7,7%) had minor manifestations of fibrosis. Pancreatoduodenal resection was performed in 2 (15,4%) patients after preliminary biliary decompression, in 2 (15,4%) – after Pjustov-Frey surgery and cystojejunostomy. Conclusion. Progression of fibroinflammatory changes in the pancreatic parenchyma in chronic pancreatitis, leading to the development of complications (biliary hypertension, duodenal stasis), is an indication for the use of resection surgery.

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The Validity of Radiological Methods in Assessment of Inflammatory Activity and Fibrous Transformation of the Pancreas at Chronic Pancreatitis

Cited by 3 publications

References 4 publications

Optimal management of early surgery of chronic pancreatitis

Optimal management of early surgery of chronic pancreatitis

Optimal time for surgical treatment of chronic pancreatitis or optimal surgery?

Pancreatoduodenal resection in the treatment of complicated forms chronic pancreatitis

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