The validity of diagnosis of melancholic depression according to different diagnostic systems1This study was presented as a poster at the `World Psychiatric Congress', Madrid, Spain, 1996.1

Türkçapar, M. Hakan; Akdemir, Ahmet; Örsel, Sibel; Demirergi, N.; Şirin, A.; Kılıç, Emine Zinnur; Ozbay, Muhammet

doi:10.1016/s0165-0327(98)00146-3

Cited by 16 publications

(4 citation statements)

References 13 publications

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“…In a study of 176 outpatients with unipolar depression, DSM-III-R criteria diagnosed more patients with melancholia (22.7%) than DSM-IV criteria (16.5%) 38. In another study of 65 patients with unipolar depression, melancholic depression was diagnosed more frequently using DSM-IV (56.9%) than DSM-III-R criteria (50.8%) 39. Thus, some misclassification was inevitable.…”

Section: Discussionmentioning

confidence: 99%

Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors

Noonan¹,

Pascoe²,

Lindén³

2013

CIA

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BackgroundDepression is common in elderly stroke survivors and has been associated with systemic inflammation. We aimed to investigate an elderly population of Swedish stroke patients for evidence of sustained peripheral inflammation 18 months post-stroke and to identify if inflammation is associated with post-stroke depression at 18 months post-stroke.MethodsThe Barthel Index was used to measure the level of impairment in activities of daily living at 3 days post-stroke. Serum concentrations of inflammation markers, ie, C-reactive protein and white cell count, were measured in 149 stroke patients (mean age 81 ± 5.33 years, 35% male) at 18 months post-stroke, and a comparison was made with an age-matched sample of elderly Swedish individuals who had not suffered a stroke. At the same visit, clinical depression was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised criteria. Severity of depression was assessed using the Montgomery-Asberg Depression Rating Scale (MADRS).ResultsMean C-reactive protein and white cell count levels in stroke patients were significantly elevated at 18 months post-stroke compared with population probands. Disability scores were associated with MADRS depression scores, but C-reactive protein and white cell count were not.ConclusionWe found evidence for a sustained peripheral inflammatory response at 18 months post-stroke. C-reactive protein and white cell count were not associated with depression in this study.

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Section: Discussionmentioning

confidence: 99%

Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors

Noonan¹,

Pascoe²,

Lindén³

2013

CIA

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“…In several checklist-based studies that examined associations between stress and melancholic and nonmelancholic depression, for example, stressful life events were found to be more strongly associated with nonmelancholic (vs. melancholic) forms of the disorder (Kohn et al, 2001;Robins, Block, & Peselow, 1990;Türkçapar et al, 1999). However, a substantial number of null findings have also been published (e.g., Leff, Roatch, & Bunney, 1970;Monroe, Thase, Hersen, Himmelhoch, & Bellack, 1985;Thomson & Hendrie, 1972).…”

Section: Depression Subtypesmentioning

confidence: 99%

Stress and its sequelae: Depression, suicide, inflammation, and physical illness.

Slavich

Auerbach

APA Handbook of Psychopathology: Psychopathology: Understanding, Assessing, and Treating Adult Mental Disorders (Vol. 1).

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“…A key problem lies in the methods used to diagnose "true melancholia" and differentiate it from non-melancholic depression, with many of the studies reviewed using criteria that may not have ensured such a distinction. On the other hand, studies published in the 80s and early 90s could be considered of higher quality at the diagnostic level, especially those using RDC criteria, as RDC criteria by many are considered closer to delimit "true melancholia" from non-melancholic (reactive) depression (46). In addition, the pragmatic choice of treating endogenous and melancholic as synonymous can be problematized as "endogenous" traditionally may imply an absence of a triggering cause (47,48).…”

Section: Advantages and Limitationsmentioning

confidence: 99%

Electroencephalographic Parameters Differentiating Melancholic Depression, Non-melancholic Depression, and Healthy Controls. A Systematic Review

Bruun¹,

Arnbjerg

Kessing

2021

Front. Psychiatry

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Introduction: The objective of this systematic review was to investigate whether electroencephalographic parameters can serve as a tool to distinguish between melancholic depression, non-melancholic depression, and healthy controls in adults.Methods: A systematic review comprising an extensive literature search conducted in PubMed, Embase, Google Scholar, and PsycINFO in August 2020 with monthly updates until November 1st, 2020. In addition, we performed a citation search and scanned reference lists. Clinical trials that performed an EEG-based examination on an adult patient group diagnosed with melancholic unipolar depression and compared with a control group of non-melancholic unipolar depression and/or healthy controls were eligible. Risk of bias was assessed by the Strengthening of Reporting of Observational Studies in Epidemiology (STROBE) checklist.Results: A total of 24 studies, all case-control design, met the inclusion criteria and could be divided into three subgroups: Resting state studies (n = 5), sleep EEG studies (n = 10), and event-related potentials (ERP) studies (n = 9). Within each subgroup, studies were characterized by marked variability on almost all levels, preventing pooling of data, and many studies were subject to weighty methodological problems. However, the main part of the studies identified one or several EEG parameters that differentiated the groups.Conclusions: Multiple EEG modalities showed an ability to distinguish melancholic patients from non-melancholic patients and/or healthy controls. The considerable heterogeneity across studies and the frequent methodological difficulties at the individual study level were the main limitations to this work. Also, the underlying premise of shifting diagnostic paradigms may have resulted in an inhomogeneous patient population.Systematic Review Registration: Registered in the PROSPERO registry on August 8th, 2020, registration number CRD42020197472.

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The validity of diagnosis of melancholic depression according to different diagnostic systems1This study was presented as a poster at the `World Psychiatric Congress', Madrid, Spain, 1996.1

Cited by 16 publications

References 13 publications

Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors

Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors

Stress and its sequelae: Depression, suicide, inflammation, and physical illness.

Electroencephalographic Parameters Differentiating Melancholic Depression, Non-melancholic Depression, and Healthy Controls. A Systematic Review

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