The Validity and Reliability of Chinese Frontal Assessment Battery in Evaluating Executive Dysfunction Among Chinese Patients With Small Subcortical Infarct

Mok, Vincent; Wong, Alexander; Yim, P. H. W.; Fu, Michael; Lam, Wynnie W. M.; Hui, A C F; Yau, Carmen; Wong, Ka Sing

doi:10.1097/01.wad.0000126617.54783.7

Cited by 54 publications

(50 citation statements)

References 30 publications

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“…Existing validation studies observed cutoffs of 11/12 for executive dysfunction in subcortical infarct (Sn: 69.2%, Sp: 87.7%, Ac: 80.6%) [9] and differentiated AD (cutoff 11/12; Sn: 77%, Sp: 87%) [2] from frontotemporal dementia (cutoff 10/11; Sn: 85–92%, Sp: 85%) [8]. The cutoff scores in our study are more similar to the normative values in an Italian population control sample [15].…”

Section: Discussionmentioning

confidence: 99%

“…Depression was assessed via the Cornell Scale for Depression in Dementia [24]. The Chinese FAB was administered to the subjects [9] during the initial visit by a single blinded rater. The Chinese FAB consists of 6 subtests: (1) conceptualization (conceptualization links between 2 objects from the same category, e.g.…”

Section: Methodsmentioning

confidence: 99%

“…These are namely: conceptualization, mental flexibility, motor programming, sensitivity to interference, inhibitory control and environmental autonomy. The Chinese version of the FAB was adapted for the Asian context, with the mental flexibility (verbal fluency) subtest being substituted by category fluency due to phonemic and linguistic differences in the languages [9]. The utility of the FAB as a useful test for frontal dysfunction is further confirmed by the correlations between the FAB scores and left callosomarginal and precentral segment regional blood flow on single photon emission computed tomography [10].…”

Section: Introductionmentioning

confidence: 99%

“…Existing validation studies report a range of cutoffs, either in the use of the FAB for detecting executive dysfunction in subcortical infarct (cutoff 11/12 [9]) or for differentiating AD from frontotemporal dementia (cutoff 11/12 [11] and 10/11 [14,17]). In a normative population control sample, a higher cutoff of 13/14 was observed [18].…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Performance of the Chinese Frontal Assessment Battery in Early Cognitive Impairment in an Asian Population

Chong

Lim

Chan³

et al. 2010

Dement Geriatr Cogn Disord

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Background: The Frontal Assessment Battery (FAB) has been shown to be useful in evaluating frontal dysfunction. There is a paucity of studies validating cutoffs in the early cognitive impairment. We aim to validate the Chinese FAB in Asian subjects with mild cognitive impairment (MCI) and early dementia. Methods: Eighty subjects with MCI and mild dementia and 100 cognitively healthy community subjects were studied. ROC analysis was done to determine the Chinese FAB’s optimal cutoff scores for age- and education-adjusted subgroups. Results: Chinese FAB scores were significantly lower in early cognitive impairment compared with cognitively normal controls. The optimal cutoff score was 12/13 (sensitivity 92%, specificity 78.7%). A similar cutoff score was obtained following age-adjustment and for subjects with <6 years’ education. Of note, the optimal cutoff for subjects with ≧6 years’ education was 13/14 (sensitivity 91.8%, specificity 70.3%), an improved diagnostic performance compared to the earlier reported 11/12 cutoff. In comparison, the Mini-Mental Status Examination (MMSE) had lower rule-out accuracy (77% sensitivity, 91.2% specificity). The combination of the Chinese FAB and MMSE was superior to either test in isolation. Conclusion: The education-adjusted Chinese FAB has good diagnostic performance, which can supplement the MMSE in early cognitive impairment evaluation with construct differences observed between the Chinese FAB and MMSE.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Diagnostic Performance of the Chinese Frontal Assessment Battery in Early Cognitive Impairment in an Asian Population

Chong

Lim

Chan³

et al. 2010

Dement Geriatr Cogn Disord

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“…Corroborating evidence comes from the validation study of the Chinese Frontal Assessment Battery, where it was reported that normal controls consistently scored lower on the similarities item (mean=0.71) compared with the other five items, including the differences item (range of means: 2.5-3.0). 84 Not uncommonly, the protectiveness towards the elderly seen in many conservative Asian families, often encourages a longstanding restricted and homebound lifestyle with little variability in their daily routines and where most tasks are taken over by their families. 5,13 In such circumstances, the utility of testing recent autobiographical memory (which involves the recall of recent events in the last 1 week and 1 month) would be limited.…”

Section: Influence Of Culture On Cdr Scoringmentioning

confidence: 99%

Utility of the Clinical Dementia Rating in Asian Populations

Lim¹,

Chong²,

Sahadevan³

2007

Clinical Medicine & Research

115

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Consistent with the worldwide demographic trend of population aging, dementia is expected to become a burgeoning public health problem in Asian populations.Thus, there is a pressing need for reliable and valid methods of dementia diagnosis and staging that are applicable in heterogeneous Asian populations. The Clinical Dementia Rating (CDR) is an informant-based global assessment scale with established reliability and validity that has been widely utilized as a severity-ranking scale in many studies of Asian populations. From a diagnostic standpoint, the CDR is congruent with the Diagnostic and Statistical Manual of Mental Disorders approach of dementia diagnosis. It exhibits excellent discriminatory ability in the very mild stages of dementia, a useful property that is germane to the surging interest in mild cognitive impairment and related concepts. Limitations of the CDR include its length of administration, reliance on clinical judgment and collateral source information, and relative insensitivity as a measure of change in interventional studies. Since the exercise of clinical judgment is inherent in scoring, CDR raters should be mindful of the influence of cultural factors on premorbid lifestyle, informant reliability and performance in certain CDR test items (especially those pertaining to the categories of judgment and problem solving, community, and home and hobbies). Thus, in future studies that involve the nascent use of the CDR in Asian populations, it is recommended that any transcultural adaptation of CDR items be described in detail and appropriate validation studies be carried out before adopting the CDR as a yardstick measure of assessment. The potential of adapted versions of the CDR in chronic care settings and advanced cases should be explored.An integrative approach, combining brief informant interview in conjunction with brief objective cognitive testing, could be a viable strategy for dementia screening in the clinical and research setting that warrants further evaluation in Asian populations.

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Rivastigmine for vascular cognitive impairment

Birks¹,

McGuinness

Craig

2013

Cochrane Database of Systematic Reviews

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The Validity and Reliability of Chinese Frontal Assessment Battery in Evaluating Executive Dysfunction Among Chinese Patients With Small Subcortical Infarct

Abstract: Although CFAB is reliable, it is only moderately valid in evaluating executive dysfunction among Chinese stroke patients with small subcortical infarct. The clinical use of CFAB in the evaluation of executive dysfunction among this group of patients cannot be recommended at this stage.

Cited by 54 publications

References 30 publications

Diagnostic Performance of the Chinese Frontal Assessment Battery in Early Cognitive Impairment in an Asian Population

Diagnostic Performance of the Chinese Frontal Assessment Battery in Early Cognitive Impairment in an Asian Population

Utility of the Clinical Dementia Rating in Asian Populations

Rivastigmine for vascular cognitive impairment

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