The Utility of Open Lung Biopsy in Patients Requiring Mechanical Ventilation

Mechanical Ventilation and Air Leaks After Lung Biopsy for Acute Respiratory Distress Syndrome

“…This value is higher than the 3% to 22% reported in previous studies of biopsy of diffuse lung disease [3][4][5][6][7], and likely due to several factors. One factor is our assumption that air leaks would have persisted in those patients who died before day 7.…”

“…The most common postoperative complication of open lung biopsy noted in several studies of patients with acute respiratory failure is prolonged air leak, with an incidence rate of 3% to 22% [3][4][5][6][7]. Identification of baseline characteristics predictive of persistent air leak may allow for better risk stratification of patients.…”

Correlation Between Surgical Lung Biopsy and Autopsy Findings and Clinical Data in Patients With Diffuse Pulmonary Infiltrates and Acute Respiratory Failure

“…Hospital mortality rates from similar but smaller series of hypoxic patients undergoing SLB are consistent with our experience, ranging from 50% to 70%. [3][4][5][6][7] In contrast, reported mortality rates for all patients (hypoxic and nonhypoxic) undergoing SLB tend to be lower. 4,[8][9][10] Greenman and coworkers 11 found a 73% mortality rate in hypoxic (PaO 2 < 55 mm Hg) immunosuppressed patients and a 39% mortality rate in nonhypoxic patients.…”

Infiltrado pulmonar no paciente crítico: a importância da biópsia pulmonar

“…Such agents include Pneumocystis carinii/jiroveci, Mycobacterium tuberculosis, other mycobacteria and Nocardia. (1)(2) In the absence of an etiological diagnosis, broad-spectrum antimicrobial treatment regimens tend to be used and are frequently extended over the course of the treatment if a satisfactory response is not obtained. These treatments expose the patients to side effects from a great number of antibiotics, increase the risk of nosocomial infection, facilitate the emergence of resistant strains, and are costly.…”