The utility of micro-ultrasound in patients under active surveillance for low-risk prostate cancer: A PRIAS study extension

Maffei, Davide; Staerman, F.; Paciotti, Marco; Colombo, Piergiuseppe; Elefante, Grazia Maria; Domanico, L.; Regis, F.; Bevilacqua, Giulio; Fasulo, Vittorio; Lazzeri, Massimo; Hurle, Rodolfo; Saita, Alberto; Casale, Paolo; Buffi, N.M.; Guazzoni, Giorgio; Lughezzani, Giovanni

doi:10.1016/s2666-1683(20)33881-7

Cited by 2 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specificity is reported in only three studies 7,31,33 (range 27.5%–45%) and all used micro-US. Eltemamy et al.…”

Section: Resultsmentioning

confidence: 99%

“…Of the 12 articles, reliable sensitivity and specificity data could be extracted from only six. 7,21,23,31–34 Sensitivity of over 80% was reported in four studies using micro-US (range 84%–93.3%) 7,21,31,33 and one study using standard TRUS. Press et al.…”

Section: Resultsmentioning

confidence: 99%

“…15,22 The sensitivity for disease detection using micro-US ranged from 84% to 93.3%. 7,21,31,33 Indeed, Maffei et al. 33 upgraded the Gleason Score to ≥ 7 cancer in 31 patients using micro-US findings alone to indicate the site of confirmatory biopsy.…”

Section: Discussionmentioning

confidence: 99%

“…This variation is a challenge for clinicians and patients when planning care pathways and when radical intervention is required. 4 The review has demonstrated that micro-US offers promise as an imaging tool comparable with mpMRI in AS with five 7,21,23,31,33 of the 12 papers included related to studies assessing the utility of this modality. However, this review has relied on data related to this emerging technique extracted from conference abstracts with only one full-text paper being eligible for inclusion.…”

Section: Discussionmentioning

confidence: 99%

“…From the QA, seven publications had a low concern of applicability for inclusion, 7,13,21,[32][33][34][35] two had a moderate concern 30,36 and two had a high concern of applicability for inclusion 23,31 within the review. The characteristics of the studies were reviewed to assess the study inclusion criteria and study design, how disease was determined, including identification of disease progression if applicable and the modality and mode of imaging used.…”

Section: Quality Assessmentmentioning

confidence: 99%

See 4 more Smart Citations

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: A systematic review

et al. 2021

View full text Add to dashboard Cite

Background The use of multiparametric magnetic resonance imaging (mpMRI) within active surveillance of prostate cancer programmes is identified by the UK National Institute for Health and Care Excellence (NICE guideline NG 131 2019) as having a role for monitoring disease. The widespread demands on mpMRI capacity may limit its use in surveillance. It is therefore timely to review the options that modern ultrasound imaging present to this cohort of patients in the monitoring of prostate cancer. Methods Between April and September 2020, 10 databases were searched to recruit studies for the review. Three reviewers evaluated the publications for inclusion. Characteristics including the inclusion criteria for the study cohort, how disease was determined, identification of disease progression, and the modality and mode of imaging used were reviewed. Given the paucity of full text articles, a meta-analysis was not possible. A narrative review was undertaken. Results In total, 12 studies, utilising the range of ultrasound parameters of B-mode, micro-ultrasound, colour Doppler, contrast ultrasound and elastography were included. The review demonstrated that micro-ultrasound offers promise as an imaging tool comparable with mpMRI. However, this is an emerging technology with limited availability. Analysis of the data further demonstrated that by combining the diagnostic features provided by multiple modes reviewed, ultrasound has a role in the diagnostic imaging of patients on active surveillance. Conclusion Providing a multiparametric approach is utilised, stable ultrasound findings may allow for increased intervals between biopsy for men on surveillance. The advent of micro-US offers promise as an imaging modality within an active surveillance pathway but requires further verification.

show abstract

“…Specificity is reported in only three studies 7,31,33 (range 27.5%–45%) and all used micro-US. Eltemamy et al.…”

Section: Resultsmentioning

confidence: 99%