The utility of intrapleural instillation of autologous blood for prolonged air leak after lobectomy

Ahmed, Aneez D.B.; Page, Richard

doi:10.1097/mcp.0b013e3282fcea76

Cited by 19 publications

(8 citation statements)

References 34 publications

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“…The mechanism of action of ABP is postulated to be two-fold - [1] the air leak is directly sealed by the formation of a clot and the blood induces pleural inflammation resulting in pleurodesis, and [2] the blood clot physically fills the pleural space [47,56]. Chambers et al [47] reviewed 10 studies, which included one prospective RCT [57] and another prospective study [48] to address the question as to whether ABP is effective for cessation of PAL.…”

Section: Autologous Blood Pleurodesismentioning

confidence: 99%

Persistent air leak - review

Sakata

Reisenauer

Kern

et al. 2018

Respiratory Medicine

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A persistent air leak (PAL) can be caused by either an alveolar-pleural fistula (APF) or bronchopleural fistula (BPF). Complications from PAL lead to an increase in morbidity and mortality, prolonged hospital stay, and higher resource utilization. Pulmonary physicians and thoracic surgeons are often tasked with the difficult and often times frustrating diagnosis and management of PALs. While most patients will improve with chest tube thoracostomy, many will fail requiring alternative bronchoscopic or surgical strategies. Herein, we review the bronchoscopic and surgical diagnostic and treatment options for PAL as it pertains to the field of interventional pulmonology and thoracic surgery.

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Section: Autologous Blood Pleurodesismentioning

confidence: 99%

Persistent air leak - review

Sakata

Reisenauer

Kern

et al. 2018

Respiratory Medicine

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“…Pleural blood patching is a simple and fast (<5 minutes) salvage maneuver used since 2008 to avoid chest tubes in the face of a growing or symptomatic pneumothorax (11,18). The technique was originally adopted from the thoracic surgery literature where large volume blood patching has been used with success to treat persistent postsurgical air leaks (26)(27)(28). The volumes of pleural blood used in the current study (median, 30 mL) were less than that used in prior surgical series (generally >100 mL) (27,28) under the presumption that a lesser volume of blood was required after biopsy due to a smaller hole in the lung surface.…”

Section: Discussionmentioning

confidence: 99%

“…The technique was originally adopted from the thoracic surgery literature where large volume blood patching has been used with success to treat persistent postsurgical air leaks (26)(27)(28). The volumes of pleural blood used in the current study (median, 30 mL) were less than that used in prior surgical series (generally >100 mL) (27,28) under the presumption that a lesser volume of blood was required after biopsy due to a smaller hole in the lung surface. The overall success rate (ie, chest tube avoidance) for pleural blood patching in this study was high at 83%, with slightly lower rates for patients with emphysema (75%).…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Lung Biopsy with Pleural and Parenchymal Blood Patching: Results and Complications from 1,112 Core Biopsies

Zlevor¹,

Mauch²,

Knott³

et al. 2021

Journal of Vascular and Interventional Radiology

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“…Reports on the use of blood pleurodesis include those by Droghetti et al [4] (retrospective cohort study, 21 patients), Ahmed et al [17] (5 patients), and Athanassiadi et al [18] (prospective cohort study, 20 patients undergoing surgery for malignant/benign causes). Özpolat [19] reported the first application of blood pleurodesis for air leakage developing after hydatid cyst operations.…”

Section: Discussionmentioning

confidence: 99%

Blood pleurodesis for air leak after pulmonary resection

Akçıl¹,

Hatipoğlu²,

Cansever³

et al. 2019

Curr Thorac Surg

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Background: Blood pleurodesis procedures were generally performed for patients with prolonged air leakage due to pneumothorax. This study investigates the use of blood pleurodesis in patients with prolonged air leak after lung resection and the variables affecting its success. Materials and Methods: A total of 493 patients who underwent anatomical lung resection for nonsmall cell lung cancer between January 2012 and December 2016 were evaluated retrospectively. 68 (13.7%) patients who underwent blood pleurodesis were included the study group. The success rate of the procedure was evaluated according to age, gender, side and type of the surgery, histopathology, and the expansion of the lungs and air leakage. Results: The success rate was not related to age, sex, side of the operation, histopathology, and type of the resection, while it was found to be statistically significant for the air leakage score (p < 0.001). The procedure was successful in 46 (67.6%) patients and failed in 22 (32.3%) patients. Conclusions: The blood pleurodesis is a safe, effective and low cost method for treatment of postoperative air leakage in patients with anatomical lung resection for primary lung carcinoma.

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The utility of intrapleural instillation of autologous blood for prolonged air leak after lobectomy

Abstract: Instillation of autologous blood into the pleural drain in the early postoperative period can lead to immediate sealing of the air leak and allow for earlier drain removal and timely patient discharge. It is a safe bed-side procedure and can be done with relative ease and at minimal cost.

Cited by 19 publications

References 34 publications

Persistent air leak - review

Persistent air leak - review

Percutaneous Lung Biopsy with Pleural and Parenchymal Blood Patching: Results and Complications from 1,112 Core Biopsies

Blood pleurodesis for air leak after pulmonary resection

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