The uterus and fertility

Taylor, E. G.; Gomel, Victor

doi:10.1016/j.fertnstert.2007.09.069

Cited by 354 publications

(253 citation statements)

References 172 publications

(179 reference statements)

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“…These lesions can affect the natural fertility beside affect pregnancy rates [21,22]. Acquired uterine lesions, such as uterine fibroids, endometrial polyps, intrauterine adhesions, or all of these, may cause infertility by interfering with proper embryo implantation and growth [3].…”

Section: Discussionmentioning

confidence: 99%

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Ali¹,

Nasr²,

Ahmed³

et al. 2017

ARC Journal of Gynecology and Obstetrics

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Section: Discussionmentioning

confidence: 99%

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Ali¹,

Nasr²,

Ahmed³

et al. 2017

ARC Journal of Gynecology and Obstetrics

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“…EPs are benign localized glandular and stromal overgrowth that represent as sessile or pedunculated lesion, may be seen single or multiple and varies in size from millimetres to centimetre (2,3,17). Based on population study, its incidence varies between 7.8% to 34.9% (18,19).…”

Section: Discussionmentioning

confidence: 99%

Histologic Features and Differential Diagnosis of Endometrial Polyps; An Update and Review

Tabrizi¹

2016

IJWHR

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IntroductionAmong the endometrial lesions, endometrial polyps (EPs) are commonly seen in the premenopausal and postmenpuasal age group and are found in 25% of endometrial specimens performed for abnormal uterine bleeding (1). EPs are generally considered as local hyperplasitic lesions of endometrial stroma which covered by epithelium. These lesions are seen single or multiple, sessile or pedunculated and the size range differs from millimetres to centimetres. In 10% of cases they mimic endocervical polyp due to prolapsus from external os (2,3). In a case of sufficient clinical, hysteroscopic and imaging information, the histologic diagnosis is usually straightforward. From clinical and prognostic standpoint, it should be emphasized that rarely these lesion may harbour premalignant and malignant lesions particularly in older age group. Therefore careful histologic examination for rule out of raised malignant lesions should be considered. In the other hand in rare cases these lesions may show metastatic involvement particularly from lobular breast carcinoma. Prevalence of these lesions in association with clinical presentation and histologic features will be presented and differential diagnosis with special emphasis on rule out of malignant lesions will be discussed. PrevalenceIn the 2402 office hysteroscopy performed on women with mean age of 39.4 years old for several indications, the prevalence of EP was 27.2% (4). Based on used diagnostic method and study group the mentioned rate varies between 6% to 32% and this rate increases with age (5-7). In another large study carried out on 686 Danish women in range of 20-79 years of old who accepted to be examined by both transvaginal sonography and saline contrast sonohysterography, the prevalence of EP was 7.8% (5). In this study the EPs were rare (0.9%) between young women and in women older than 30 years the prevalence was 9.2%. EPs are rarely found in OCP user whereas in the women who were on hormone replacement therapy the prevalence was much higher (2.1% vs. 25%) (5). Respect to hormones as an etiologic factor, high frequency of endometrial hyperplasia was found in the non-polyploid region of endometrium in premenopausal and postmenopausal women (8). Clinical PresentationThe usual clinical presentations of EPs may include menorrhagia, intermenstrual bleeding, postmenopausal bleeding and infertility. However the majority of patients may be asymptomatic and the prevalence could be similar in symptomatic and asymptomatic women (5). These findings indicates that there is no consistent relationship between abnormal uterine bleeding and existence of EPs and why hysteroscopic resection of EPs does not always result in relief of symptoms (9). A pathologist should be alert that in the most cases of protruded EPs, the usual clinical diagnosis will be endocervical polyp by the gynaecologist. Regard to tamoxifen, EPs are the most common pathology that could be seen in these patients. In these patients the prevalence of AbstractAmong the endometrial lesions, endometrial poly...

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“…Özellikle IVF'e gidecek hastaların cerrahi ön-cesi, düşük yapmalarını beklemek endoskopik cerrahinin sonuçlarının bu kadar iyi, komplikasyonlarının bu kadar az olması göz önüne alındı-ğında, yapılmış çalışmalar neticesinde, günümüzde pek uygulanabilecek bir protokol olmamalıdır. [13][14][15] Endoskopik cerrahi sonuçlarının bu kadar iyi, komplikasyonlarının bu kadar az olması gözönüne alındığında IVF öncesi, septum insizyonunun rutin yapılması kaçınılmaz bir gerçektir.…”

Section: Primer Infertilunclassified

The Effect of Hysterescopic Uterine Septum Surgery on Pregnancy Rates

Cömert¹,

Çetin²,

Çetin³

et al. 2017

TJRMS

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A Am ma aç ç: : Primer infertilite, tekrarlayan gebelik kaybı, preterm doğum öyküsü veya sekonder infertilite tanısı ile kliniğimize başvuran ve uterin septum tespit edilen olgularda, histeroskopik cerrahi müdahale sonrası gebelik sonuçlarının incelenmesi amaçlanmıştır. G Ge er re eç ç v ve e Y Yö ön n--t te em ml le er r: : Ocak 2008-Aralık 2014 tarihleri arasında Çukurova Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği İnfertilite Polikliniğine primer infertilite, tekrarlayan gebelik kaybı, preterm doğum öyküsü veya sekonder infertilite tanısı ile başvuran ve histerosalpingografide uterin septum tespit edilen 118 hasta çalışmaya dahil edildi. Tüm olgulara genel anestezi altında laparoskopi eşliğinde histeroskopik septum insizyonu uygulandı. Hastalar postop 24 ay gebelik açısından takip edildi. B Bu ul lg gu ul la ar r: : Hastaların 48'i (%40,6) primer infertil, 70'i (%59,3) sekonder infertildi. 44 (%37,2) hastanın komplet septumu, 74 (%62,7) hastanın inkomplet septumu mevcuttu. Toplam 118 hastanın operasyon sonuçları 84 (%71,1)'sı gebe kaldı, 34 (%28,8)'sında gebelik oluşmadı.Toplam gebelik sayısı 164 idi. Bunun 28 (%17)'i spontan abortus, 23 (%14)'i preterm doğum, 113 (%68,9)'i term doğum olarak saptandı. 118 hastadan toplam doğum yapan hasta sayısı 74 (%62,7) bulundu. Toplam preterm ve term doğum sayısı; komplet septumu olan 44 hastadan 30 (%68,1)'unda, inkomplet septumu olan 74 hastadan 54 (%72,9)'ünde tespit edildi. S So on nu uç ç: : Uterus septumun tekrarlayan in vitro fertilizasyon (IVF) başarısızlığı, düşük, preterm eylem gibi gebelik kayıplarıyla ilişkili olduğu bilinmektedir. Uterin septumun histeroskopik insizyonu kolay uygulanabilir ve gebelik sonuçları üzerine olumlu etkileri olan bir yöntemdir.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Histeroskopik cerrahi; infertilite; gebelik sonuçları A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : The pregnancy outcomes after the hyteroscopic surgery of the patients who presented with primary/secondary infertility, recurrent pregnancy loss and preterm birth and who were diagnosed with uterine septum, were aimed to be evaluated. M Ma at te er ri ia al ls s a an nd d M Me et th ho od ds s: : 118 patients who presented to Cukurova University Medical School Department of Obstetrics and Gynecology Infertility Clinic between January 2008 and December 2014 and who presented with primary/secondary infertility, recurrent pregnancy loss and preterm birth and who were diagnosed with uterine septum with the hysterosalpingography were admitted to the study. All patients had laparoscopy together with hysteroscopic septum incision under general anesthesia. Patients were followed up for 24 months for pregnancy. R Re es su ul lt ts s: : 48 patients (40.6%) had primary infertility, 70 patients (59.3%) had secondary infertility. 44 patients (37.2%) had complete septum and 74 patients had incomplete septum (62.7%). 84 patients (71.1%) got pregnant, but 34 patients (28.8%) could not get pregnant after the surgery. Total pregnancy number was ...

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The uterus and fertility

Cited by 354 publications

References 172 publications

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Histologic Features and Differential Diagnosis of Endometrial Polyps; An Update and Review

The Effect of Hysterescopic Uterine Septum Surgery on Pregnancy Rates

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