The Uterine Flap: An Option for Autogenous Repair of Perineal Hernia after Abdominoperineal Resection

Hall, David J.; Shaw, Christiana; Iqbal, Atif; Tan, Sanda

doi:10.1177/000313481708300821

Cited by 2 publications

(1 citation statement)

References 4 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ionophore antibiotics such as monensin are widely used in cattle industries for control of coccidiosis and improved feed efficiency (28). Monensin is considered safe in cattle when it is fed at recommended dosages, although it may become unsafe if higher concentrations are fed or mixing errors occur (24,29). Because of the mechanism of interfering with the cation membrane transport, the ionophores can cause cell death by destabilizing cell membranes, particularly in skeletal and cardiac muscle (30).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Two Commercially Available Immunoassays for the Measurement of Bovine Cardiac Troponin I in Cattle With Induced Myocardial Injury

Smith

Varga²,

Schober

2020

Front. Vet. Sci.

View full text Add to dashboard Cite

Background: Multiple cardiac troponin I (cTnI) immunoassays are commercially available. Overall, assays have not been standardized, and inter-assay differences in the detection of the analyte cardiac troponin I can be clinically relevant. Objective: To compare the diagnostic accuracy of the commercially available Abbott i-STAT ® 1 cTnI immunoassay (i-STAT) and the previously validated ADVIA Centaur TnI-Ultra immunoassay (Centaur) in cattle. Hypothesis: There will be significant differences in bovine serum cTnI results measured by the Centaur and i-STAT methods. Animals: Ten dairy cows with experimentally induced myocardial injury due to monensin administration. Thirty apparently healthy dairy cows with no history of monensin exposure served as controls. Methods: Blood was collected at various time points after administration of a single dose of monensin (20 to 50 mg/kg) via orogastric tube. A total of 112 blood samples were collected. Cardiac TnI concentration was analyzed with the two methods and the association between methods analyzed via linear regression. Bland-Altman analysis to evaluate agreement between methods was performed on samples divided into groups (cTnI < 1.0 ng/mL and cTnI ≥ 1.0 ng/mL). Results: Analyzer results were linearly correlated with each other (R 2 = 0.931). Samples with cTnI concentrations <1.0 ng/mL had a bias of −0.13 ± 0.20 ng/mL and samples with cTnI concentrations >1.0 ng/mL had a bias of −9.81 ± 13.26 ng/mL. Conclusions and clinical importance: The results of this study reveal that cTnI concentrations determined with the i-STAT are systematically lower compared to the concentrations determined by the Centaur.

show abstract

Section: Introductionmentioning

confidence: 99%