The usefulness of contrast during exercise echocardiography for the assessment of systolic pulmonary pressure

Lopes, Luís Rocha; Loureiro, María José; Miranda, Rita; Almeida, Sofia; Almeida, Ana Rita; Cordeiro, A.; Cotrim, Carlos; Carrageta, Manuel

doi:10.1186/1476-7120-6-51

Cited by 18 publications

(15 citation statements)

References 12 publications

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“…37 In people, this has been described as a valuable tool to better visualize tricuspid regurgitation and of particular utility in the assessment of PH. 38 However in the present study, even with the aid of SonoVue Ò , tricuspid regurgitation could not be measured in any of the dogs at any examination point. Considering the expense of this substance, and being unaware of a clinically relevant indication we do not recommend this substance to be used in daily practice at the present time.…”

Section: Discussionmentioning

confidence: 75%

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

Matos

Schnyder

Bektas

et al. 2012

Journal of Veterinary Cardiology

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Section: Discussionmentioning

confidence: 75%

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

Matos

Schnyder

Bektas

et al. 2012

Journal of Veterinary Cardiology

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“…Contrast echocardiography may solve this problem. 37 In addition, invasive catheterization may be necessary.…”

Section: Study Populationmentioning

confidence: 99%

H<sub>2</sub>FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese　― Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing ―

Takahari

Hidaka

Ueda

et al. 2019

Circ J

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Background: Both the H2FPEF-score and nomogram-score, which consist of simple clinical parameters, can assist in diagnosing "early" heart failure with preserved ejection fraction (HFpEF) and only exertional dyspnea, but their these usefulness in Japanese remains unclear. We sought to investigate the correlation between these scores and exercise response, including the peak oxygen uptake (V O2), the pulmonary artery systolic pressure (PASP), the ratio of early diastolic transmitral flow velocity to early diastolic mitral annular velocity (E/e') and stroke volume (SV) using exercise stress echocardiography (ESE) combined with cardiopulmonary exercise testing (CPET). Methods and Results: In this single-center, retrospective cross-sectional study the H2FPEF-score and nomogram-score were calculated in a total of 139 patients who underwent ESE combined with CPET. The scores correlated with peak V O2 (r=−0.48, r=−0.44), PASP (r=0.23, r=0.29) and SV (r=−0.32, r=−0.19) at peak exercise. The nomogram-score correlated with E/e' (r=0.24). The prevalence of exercise intolerance (percent predicted peak V O2 <75% and <50%) increased as the H2FPEF-score increased and reached 88.9% and 22.2% among the patients with high H2FPEF-score (6-9 points). Conclusions: The H2FPEF-score may be useful as the initial step to diagnosing 'early' HFpEF. The nomogram-score may be more useful in Japanese because of its more universal association with exercise response than the H2FPEF-score.

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“…RVSP had no impact on predisposition to adverse outcomes in patients undergoing contrast echocardiography. Moreover, contrast agents may represent a valuable tool for the assessment of pulmonary systolic pressure [49]. All these clinical data are in accordance with experimental models in pulmonary hypertensive dogs who received the agent Optison in usual human doses [50].…”

Section: Clinical Datamentioning

confidence: 68%

Ultrasound Contrast Agents: Updated Data on Safety Profile

Aggeli

Felekos²,

Siasos³

et al. 2012

CPD

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Contrast echocardiography represents a major technological advancement in the constantly evolving field of cardiovascular imaging. Over the last twenty years numerous studies have been published, illustrating the incremental value of contrast implementation into a variety of clinical scenarios. However, serious concerns have been raised about contrast safety profile, mainly based on postmarketing observational data and several animal studies. The latter have investigated contrast bio effects under experimental conditions that are not consistent with daily clinical practice. On the other hand, numerous clinical trials with large registries have proven otherwise. Not only contrast agents are efficient, but they also demonstrate a remarkable safety profile. So the question is: should we fear contrast utilization or should we consider them as an adjunctive and indispensable clinical tool for daily bedside practice?

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The usefulness of contrast during exercise echocardiography for the assessment of systolic pulmonary pressure

Abstract: Background: The systolic pulmonary artery pressure (PAPs) can be accurately estimated, noninvasively, using continuous-wave Doppler (CWD) ultrasound measurement of the peak velocity of a tricuspid regurgitant (TR) jet.

Cited by 18 publications

References 12 publications

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

H<sub>2</sub>FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese　― Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing ―

Ultrasound Contrast Agents: Updated Data on Safety Profile

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The usefulness of contrast during exercise echocardiography for the assessment of systolic pulmonary pressure

Abstract: Background: The systolic pulmonary artery pressure (PAPs) can be accurately estimated, noninvasively, using continuous-wave Doppler (CWD) ultrasound measurement of the peak velocity of a tricuspid regurgitant (TR) jet.

Cited by 18 publications

References 12 publications

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

Recruitment of arteriovenous pulmonary shunts may attenuate the development of pulmonary hypertension in dogs experimentally infected with Angiostrongylus vasorum

H<sub>2</sub>FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese ― Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing ―

Ultrasound Contrast Agents: Updated Data on Safety Profile

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Product

Resources

About

H<sub>2</sub>FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese　― Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing ―