Abstract:Introduction. Psoriasis is a chronic inflammatory disorder with a genetic and environmental background. The use of biological agents in cases of refractory psoriasis and psoriatic arthritis proved to be a breakthrough due to their effectiveness and safety profile. An indication for biological agents, apart from the lack of therapeutic effect, is the occurrence of side effects during conventional treatment. Commonly used systemic therapies are associated with occurrence of a cumulative toxic effect that require… Show more
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