The use of ultrasound in schistosomiasis

Hatz, Christoph

doi:10.1016/s0065-308x(01)48007-9

Cited by 102 publications

(62 citation statements)

References 154 publications

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“…The prevalence of pathological changes is not always associated with egg output or laboratory tests; it is possible that disease is present, but that Schistosoma mansoni eggs are not being excreted and remain trapped in fibrous lesions 12 . Previous studies on experimental animals have estimated that 50% of the eggs are retained in tissues, especially in the liver 33 .…”

Section: Discussionmentioning

confidence: 99%

Clinical and ultrasound findings before and after praziquantel treatment among Venezuelan schistosomiasis patients

Ruiz-Guevara

Noya

Valero

et al. 2007

Rev. Soc. Bras. Med. Trop.

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Section: Discussionmentioning

confidence: 99%

Clinical and ultrasound findings before and after praziquantel treatment among Venezuelan schistosomiasis patients

Ruiz-Guevara

Noya

Valero

et al. 2007

Rev. Soc. Bras. Med. Trop.

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“…The morbidity associated with schistosomiasis and soiltransmitted helminths is well documented in the biomedical literature (see, for example, Berquist, 2002;King et al, 2005;Molyneux et al, 2005;Hotez et al, 2005Gryseels et al, 2006;Brown, 2011;Chen et al, 2012). Schistosomosa heamatobium infection involves pathological changes to the renal and reproductive organs (Blum et al, 1998;Hatz, 2001;Gryseels et al, 2006). Both schistosomiasis and soil-transmitted helminths -particularly hookworm -can result in chronic iron deficiency anaemia due to blood loss (Lwambo et al, 1999;Hotez et al, 2005).…”

Section: Rejection Of Mass Drug Administration In Tanzania S17mentioning

confidence: 99%

Rumours, Riots and the Rejection of Mass Drug Administration for the Treatment of Schistosomiasis in Morogoro, Tanzania

Hastings

2016

J. Biosoc. Sci.

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SummaryIn 2008 in Morogoro region, Tanzania, mass drug administration (MDA) to school-aged children to treat two neglected tropical diseases (NTDs) – urinary schistosomiasis and soil-transmitted helminths – was suspended by the Ministry of Health and Social Welfare after riots broke out in schools where drugs were being administered. This article discusses why this biomedical intervention was so vehemently rejected, including an eyewitness account. As the protest spread to the village where I was conducting fieldwork, villagers accused me of bringing medicine into the village with which to ‘poison’ the children and it was necessary for me to leave immediately under the protection of the Tanzanian police. The article examines the considerable differences between biomedical and local understandings of one of these diseases, urinary schistosomiasis. Such a disjuncture was fuelled further by the apparent rapidity of rolling out MDA and subsequent failures in communication between programme staff and local people. Rumours of child fatalities as well as children’s fainting episodes and illnesses following treatment brought about considerable conjecture both locally and nationally that the drugs had been either faulty, counterfeit, hitherto untested on humans or part of a covert sterilization campaign. The compelling arguments by advocates of MDA for the treatment of NTDs rest on the assumption that people suffering from these diseases will be willing to swallow the medicine. However, as this article documents, this is not always the case. For treatment of NTDs to be successful it is not enough for programmes to focus on economic and biomedical aspects of treatment, rolling out ‘one size fits all’ programmes in resource-poor settings. It is imperative to develop a biosocial approach: to consider the local social, biological, historical, economic and political contexts in which these programmes are taking place and in which the intended recipients of treatment live their lives. If this is not done, the world’s poor will continue to be neglected.

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“…Whilst clinical investigations with ultrasound and/or abdominal palpation methods can better describe morbidity associated with Schistosoma mansoni infection, for example hepatosplenomegaly, liver fibrosis and/or organ texture (Hatz, 2001;King et al, 2003), these require specialist equipment and well trained staff (Nooman et al, 1995;Ruiz et al, 2002). As a consequence, large-scale community screening of morbidity has been limited and broad geographic comparisons are rarely made.…”

Section: Introductionmentioning

confidence: 99%

Morbidity due to Schistosoma mansoni: an epidemiological assessment of distended abdomen syndrome in Ugandan school children with observations before and 1-year after anthelminthic chemotherapy

Balen

Stothard

Kabatereine

et al. 2006

Transactions of the Royal Society of Tropical Medicine and Hygi

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The use of ultrasound in schistosomiasis

Cited by 102 publications

References 154 publications

Clinical and ultrasound findings before and after praziquantel treatment among Venezuelan schistosomiasis patients

Clinical and ultrasound findings before and after praziquantel treatment among Venezuelan schistosomiasis patients

Rumours, Riots and the Rejection of Mass Drug Administration for the Treatment of Schistosomiasis in Morogoro, Tanzania

Morbidity due to Schistosoma mansoni: an epidemiological assessment of distended abdomen syndrome in Ugandan school children with observations before and 1-year after anthelminthic chemotherapy

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