A study was conducted in the western highland region of Cameroon with the aim to assess sustainability of Gnidia glauca exploitation in its natural habitat. In 33 plots of 40 x 40 m, the unexploited, exploited and dead trees were evaluated for vitality using a multi-criteria vulnerability assessment method. An ethnobotanical survey was conducted with 60 respondents in six villages around Mount Oku area. Data were submitted to ANOVA and means separated using Duncan test. The results revealed that 95 % of G. glauca trees were unexploited and only 3.92% showed signs of exploitation, among which 1.08% were dead. Among the exploited stems, 18% showed a completely dead crown, whereas 73% were described to be regular and healthy. Wood (29%) and bark (28%) were the main products being exploited. However, the species' bark was the most frequently harvested product (64%). G. glauca was shown to be more vulnerable in forests (2.6) than in savanna (2.4). The motivating factors for the species' domestication were the fragility of its habitat, the potential high future demand for its products and the unsustainable exploitation techniques being applied. It is therefore recommended to promote the species uses, conservation and cultivation within its national distribution range for local livelihood improvement.