The use of the esterified fatty acid index in the classification and quantitation of hyperlipoproteinaemias

Billimoria, J. D.; Fahmy, Maurice; Jepson, E.; Maclagan, N. F.

doi:10.1016/0021-9150(71)90064-5

Cited by 10 publications

(5 citation statements)

References 25 publications

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“…In general the diabetics show a pattern of class P or class PB according to our classification (Billimoria et al, 1971) or type IV or type II B with slightly more raised triglyceride on the Fredrickson classification. In our experience this type of hyperlipoproteinaemia is well controlled by treatment with clofibrate.…”

Section: Resultsmentioning

confidence: 98%

A Lipid and Lipoprotein Profile of Treated and Untreated Diabetics

1976

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A group of 149 diabetics and 98 healthy subjects without evidence of diabetes or ischaemic heart disease were studied. Untreated diabetics under 40 years old and 40 years of age and over showed statistically raised fasting serum turbidity, triglycerides, and raised beta and pre-beta lipoprotein levels but not raised cholesterol levels over the age and sex matched normal subjects. Further, some 63% of all diabetics showed a distinct split pre-beta lipoprotein pattern as seen on polyacrylamide disc electrolphoresis as compared with 17% in the control group. Raised lecithin and phosphatidylethanolamine (PE) levels were found in male diabetics and raised PE levels in young diabetic women. In patients under treatment with insulin, chlorpropamide, or phenformin the diabetes was well controlled in most cases, but these patients did not have significantly lower lipid levels. Diabetics on a low carbohydrate diet showed improvement in triglycerides and pre-beta lipoprotein levels, but beta lipoproteins were not lowered. It is suggested that diabetics may benefit by the inclusion of clofibrate in the treatment.

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Section: Resultsmentioning

confidence: 98%

A Lipid and Lipoprotein Profile of Treated and Untreated Diabetics

1976

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“…scribed (Billimoria et al 1971). Total phospholipids, and phospholipid fractions after separation by thin-layer chromatography (TLC) (Skipski et al 1962), were estimated by a modification of a standard method (Bartlett 1959).…”

Section: Methodsmentioning

confidence: 99%

“…Lipoprotein electrophoresis was carried out on cellulose acetate and the esterified fatty acid index (EFI) of each lipoprotein band estimated as previously described (Billimoria et al 1971(Billimoria et al , 1975.…”

Section: Methodsmentioning

confidence: 99%

Effect of Piperazine Oestrone Sulphate on Serum Lipids and Lipoproteins in Menopausal Women

Isaacs

Havard

1977

Acta Endocrinologica

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Twenty menopausal women and 2 women with gonadal dysgenesis were treated with piperazine oestrone sulphate 1.5\p=n-\3 mg daily on a cyclical basis for a period of 6 months. Fasting serum lipids and lipoprotein esterified fatty acid indices (EFI) were estimated before starting treatment and after 3 and 6 months. There were small falls in serum cholesterol (significant at 3 months) and beta-lipoprotein EFI (significant at 6 months). Serum triglyceride and pre-beta-lipoprotein EFI rose significantly at both 3 and 6 months. Serum total phospholipid levels were reduced (significant at 6 months) with most marked changes in the sphingomyelin fraction. Other parameters were not significantly altered.

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“…It is not absorbed through food having an important role in the body. It is the precursor to various processes produced in body [1][2][3]. In excess, cholesterol (cholesterolemia) leads to vascular diseases: cerebrovascular, cardiac, ocular, very life-threatening accidents.…”

Section: Introductionmentioning

confidence: 99%

Cholesterol in Human Body: Importance and Dosage

GÎRBOIU,

MUREŞAN

2023

Ann_UGAL_MMS

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For a healthy life, specialists recommend us to take care of what food we eat and to what extent we do it and how we approach a satisfying lifestyle. Cholesterol is not a bad thing, but often, in large quantities it becomes dangerous for human body. The medical world is faced with frequent changes in the concept of "normal values" of cholesterol, but also with a continuously developing pharmaceutical industry in this field, and the tendency is in this sense, towards an individualized treatment. This aspect in presented in our paper, which aims to describe the role of cholesterol in the functioning of human body; preventing the occurrence of heart diseases due increasing the level of cholesterol in the body and creating a healthy lifestyle that can reduce cholesterol levels. The paper presents some case studies on laboratory investigations of values cholesterol that includes determinations, studying and the research of medical equipment (Cobas Integra 400 Plus analyser), but also the results obtained during practice in the medical analysis laboratory.

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The use of the esterified fatty acid index in the classification and quantitation of hyperlipoproteinaemias

Cited by 10 publications

References 25 publications

A Lipid and Lipoprotein Profile of Treated and Untreated Diabetics

A Lipid and Lipoprotein Profile of Treated and Untreated Diabetics

Effect of Piperazine Oestrone Sulphate on Serum Lipids and Lipoproteins in Menopausal Women

Cholesterol in Human Body: Importance and Dosage

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