The Use of the Complement-Fixation Reaction in the Diagnosis of Human Psittacosis

Chlamydial infections in feral pigeons in Europe: Review of data and focus on public health implications

“…The test was originally described by Bedson (1935), and it 343 can be used for analysing sera from pigeons, as recommended by Page (1975) which is more sensitive than the CFT, easier to standardize and more suitable for large-scale 353 epidemiological studies, has been also recommended (Schmeer, 1983;Fudge, 1991). several PCR protocols were applied, with genomic targets as diverse as the ompA, the 16S rRNA 377 and the 23S rRNA genes, which allowed the detection of C. psittaci in 3.4 -50 % of the samples.…”

An Outbreak of Psittacosis in Pigeons, Involving the Production of Inclusion Bodies, and Transfer of the Disease to Man

“…Infection with the virus of psittacosis gives rise to antibodies that fix complement in the presence of psittacosis antigen (14). This serological reaction appears to be specific for the psittacosis-lymphogranuloma venereum group of viruses even though it fails to differentiate sharply between individual members of the family (3)(4)(5)(6)(7)(8).…”

Detection of Chlamydia psittaci using DNA probes and the polymerase chain reaction

“…Human chlamydial infections are most commonly diagnosed by isolation in cell culture [4], the complement fixation test [5], ELISA [6] or fluorescent antibody staining [7]. Provided they are accurately diagnosed, chlamydial infections can be treated adequately with antibiotics.…”

“…However, they are often misdiagnosed and this may lead to serious disease. Human chlamydial infections are most commonly diagnosed by isolation in cell culture [4], the complement fixation test [5], ELISA [6] or fluorescent antibody staining [7]. Cell culture has been considered the most sensitive and specific technique, however methods which do not rely on the viability of the chlamydiae are preferable.…”