“…In this experimental evaluation with human corneas we observed that the optically measured central ablation depth was significantly higher than the calculated depth. Also with US [12,22] and optically [9,20,37], significantly more tissue was ablated than predicted, which most probably is due to dehydration of the corneal stroma [9,11,30] or other laser-tissue interactions [4,18] occurring during excimer laser ablation. It seems that the effects on corneal tissue from dehydration can be caused from exposure to air with evaporation and consequent thinning, which has been found to be dramatic in some cases, ranging from 10% to 13% in the normal, epithelialized cornea in a 10-min period [10,35] and up to 28.5% after 50-60 min [7,33].…”