The use of sugammadex in an infant with prolonged neuromuscular blockade - A case report -

Abstract

Background: Residual neuromuscular blockade (RNMB) is a frequent event after general anesthesia, which can lead to serious complications, such as upper airway obstruction. Sugammadex is useful in reversing RNMB. However, its use in infants has not yet been approved by the Food and Drug Administration. Therefore, anesthesiologists can be hesitant use it, even in situations where no other choice is available.Case: A two-month-old baby presented to the hospital for umbilical polypectomy. At the end of the surgery, neostigmine was administered. Even after waiting for 30 min and injecting an additional dose of neostigmine, neuromuscular blockade was not adequately reversed. Eventually, sugammadex was administered, and spontaneous breathing returned.Conclusions: If there were no particular causes of delayed return to spontaneous breathing in infants, RNMB should be considered and reversal with sugammadex would be useful.

Sugammadex in pediatric patients

“…There are many reports on the usefulness of sugammadex in pediatric patients. We read with great interest the paper titled “The use of sugammadex in an infant with prolonged neuromuscular blockade - A case report -” [ 1 ]. However, we have some concerns that we would like to discuss.…”