The Use of Speckle Correlation Analysis to Determine Blood Flow Velocity

Savchenko, Ekaterina; Velichko, Elena

doi:10.1134/s0030400x2007019x

Cited by 11 publications

(2 citation statements)

References 22 publications

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“…To process the obtained signals, we calculate the normalized autocorrelation function of the intensity fluctuations of the scattered light. The correlation function in the case of blood microcirculation detection, where the scatterer is erythrocytes in the bloodstream, is described by the following expression [ 18 ]:

where ϑ is the speed of the scatterer, l is the distance from the scattering object to the photodetector,

is wavelength of light from the light source,

and

are z-dependent width and curvature of the wave front of the beam. We denote by K the proportionality coefficient determined by the parameters of the optical circuit:

where

.…”

Section: Methodsmentioning

confidence: 99%

Joint Methodology Based on Optical Densitometry and Dynamic Light Scattering for Liver Function Assessment

et al. 2023

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A pressing health problem, both in clinical and socio-economic terms, is the increase in the number of patients with liver damage caused by viral diseases (hepatitis), cancer, toxicological damage, or metabolic disorders. Liver function assessment is a complex task, for which various existing diagnostic methods are used. Unfortunately, they all have several limitations which frequently make prompt and accurate diagnosis impossible. The high level of disability and mortality caused by liver diseases makes the development of new liver diagnostic methods very urgent. In this paper, we describe a new joint methodology for studying liver function based on optical densitometry and dynamic light scattering. This will help to diagnose and predict the dynamics of liver function during treatment with greater efficiency, due to including in consideration the individual characteristics of the cardiovascular system and tissue metabolism. In this paper, we present a laboratory model of a combined sensor for optical densitometry and dynamic light scattering. We also developed special software for controlling the sensor and processing the recorded data. Modeling experiments and physical medical studies were carried out to adjust and calibrate the sensor and software. We also assessed the sensor resolution when registering the concentration of dye in the human body and the minimum measured flow rate.

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where ϑ is the speed of the scatterer, l is the distance from the scattering object to the photodetector,

is wavelength of light from the light source,

and

are z-dependent width and curvature of the wave front of the beam. We denote by K the proportionality coefficient determined by the parameters of the optical circuit:

where

.…”

Section: Methodsmentioning

confidence: 99%

Joint Methodology Based on Optical Densitometry and Dynamic Light Scattering for Liver Function Assessment

et al. 2023

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“…When diagnosing vascular function in pregnancy, it is important first and foremost to consider maternal and fetal safety, so the use of safe and noninvasive diagnostic methods is preferable. The best prospects in this aspect are presented by methods of biophotonics [4,5]. Endothelial dysfunction seen in the skin of patients with type 1 DM is known to precede the development of target organ microcirculatory disorders.…”

Section: Introductionmentioning

confidence: 99%

Skin Blood Perfusion and Fluorescence Parameters in Pregnant Women with Type 1 Diabetes Mellitus

Zharkikh¹,

Loktionova²,

Zherebtsova

et al. 2021

2021 International Conference on Electrical Engineering and Photonics (EExPolytech)

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This work represents the first stage of a study of microcirculation and oxidative metabolism parameters in the skin of women with type 1 diabetes mellitus in early stages of pregnancy. Laser Doppler flowmetry and fluorescence spectroscopy were used to record the diagnostic parameters in the study. The main parameters of LDF recordings of patients under the study (index of microcirculation in the upper and lower extremities, normalised amplitudes of blood flow oscillations), as well as normalised fluorescence values when excited with 365 nm light, were measured and presented.

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Investigation of Self-organized Protein Films Formed Under an External Electric Field

Baranov

Rozov

Dicky

2022

Springer Proceedings in Physics

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The Use of Speckle Correlation Analysis to Determine Blood Flow Velocity

Cited by 11 publications

References 22 publications

Joint Methodology Based on Optical Densitometry and Dynamic Light Scattering for Liver Function Assessment

Joint Methodology Based on Optical Densitometry and Dynamic Light Scattering for Liver Function Assessment

Skin Blood Perfusion and Fluorescence Parameters in Pregnant Women with Type 1 Diabetes Mellitus

Investigation of Self-organized Protein Films Formed Under an External Electric Field

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